Yang Y Y
Acta Psychiatr Scand. 1985 Feb;71(2):171-5. doi: 10.1111/j.1600-0447.1985.tb01267.x.
One hundred and one bipolar patients with at least two episodes during the 2 successive years prior to lithium received continuous lithium treatment for 2 years. The prophylactic efficacy of lithium increased from 60% to 73% when patients with individual standard deviations of plasma lithium of more than 0.2 mM/l were excluded. Most of the good responders showed individual mean plasma lithium levels from 0.5 mM/l to 0.79 mM/l.
101例双相情感障碍患者在接受锂盐治疗前连续两年内至少有两次发作，接受了为期两年的持续锂盐治疗。当排除血浆锂个体标准差超过0.2 mM/l的患者后，锂盐的预防疗效从60%提高到73%。大多数治疗有效者的个体血浆锂平均水平为0.5 mM/l至0.79 mM/l。
