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新生儿体外膜肺氧合治疗气胸和支气管胸膜瘘:一例报告

Treatment of pneumothorax and bronchopleural fistula by extracorporeal membrane oxygenation in a neonate: a case report.

作者信息

Zhang Taining, Wang Jianxiu, Zhou Bingyin, Yan Bin, Chen Xilong, Wang Yanxia, Wang Weikai

机构信息

Department of Pediatric Intensive Care Unit, Gansu Provincial Maternity and Child Care Hospital, Lanzhou, Gansu, China.

出版信息

Front Pediatr. 2024 Dec 23;12:1466852. doi: 10.3389/fped.2024.1466852. eCollection 2024.

DOI:10.3389/fped.2024.1466852
PMID:39764165
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11701141/
Abstract

Intractable pneumothorax secondary to bronchopulmonary fistula is a rare complication in neonates. We present the first report of a newborn with spontaneous pneumothorax and bronchopleural fistula treated with extracorporeal membrane oxygenation (ECMO). Positive pressure mechanical ventilation resulted in persistent air leakage from the bronchopleural fistula. When ECMO was initiated, a "total lung rest" ventilation strategy was used to facilitate the healing of bronchopleural fistula and the absorption of the pneumothorax. ECMO is an effective supportive therapy for neonate pneumothorax and bronchopulmonary fistula when conventional ventilation management fails.

摘要

继发于支气管肺瘘的难治性气胸是新生儿罕见的并发症。我们首次报告了一名患有自发性气胸和支气管胸膜瘘的新生儿接受体外膜肺氧合(ECMO)治疗的病例。正压机械通气导致支气管胸膜瘘持续漏气。启动ECMO时,采用“全肺休息”通气策略以促进支气管胸膜瘘的愈合和气胸的吸收。当传统通气管理失败时,ECMO是治疗新生儿气胸和支气管肺瘘的有效支持疗法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7922/11701141/2e30194bf426/fped-12-1466852-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7922/11701141/57b7d1c3acb4/fped-12-1466852-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7922/11701141/f060af960dce/fped-12-1466852-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7922/11701141/94a3b8a9dc38/fped-12-1466852-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7922/11701141/827d1f7b833e/fped-12-1466852-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7922/11701141/55210cfff30c/fped-12-1466852-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7922/11701141/2e30194bf426/fped-12-1466852-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7922/11701141/57b7d1c3acb4/fped-12-1466852-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7922/11701141/f060af960dce/fped-12-1466852-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7922/11701141/94a3b8a9dc38/fped-12-1466852-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7922/11701141/827d1f7b833e/fped-12-1466852-g004.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7922/11701141/2e30194bf426/fped-12-1466852-g006.jpg

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本文引用的文献

1
Bronchopleural fistula management in a pediatric patient requiring extracorporeal membrane oxygenation.一名需要体外膜肺氧合的儿科患者的支气管胸膜瘘处理
Perfusion. 2025 May;40(4):1049-1053. doi: 10.1177/02676591241268367. Epub 2024 Jul 26.
2
Positive- vs. negative-pressure extubation technique: a scoping review.正压与负压拔管技术:一项范围综述
Front Med (Lausanne). 2023 May 12;10:1169879. doi: 10.3389/fmed.2023.1169879. eCollection 2023.
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Negative Pressure Is the Positive Way to Breathe!负压呼吸是积极有效的呼吸方式!
Am J Respir Crit Care Med. 2023 Mar 1;207(5):505-506. doi: 10.1164/rccm.202210-1862ED.
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Positive- and Negative-Pressure Ventilation Characterized by Local and Global Pulmonary Mechanics.局部和整体肺力学特征的正负压通气。
Am J Respir Crit Care Med. 2023 Mar 1;207(5):577-586. doi: 10.1164/rccm.202111-2480OC.
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Positive versus negative pressure during removal of endotracheal-tube on prevention of post-extubation atelectasis in ventilated neonates: A randomized controlled trial.气管插管拔除时正压与负压对预防机械通气新生儿拔管后肺不张的影响:一项随机对照试验
Ann Med Surg (Lond). 2022 Apr 4;76:103573. doi: 10.1016/j.amsu.2022.103573. eCollection 2022 Apr.
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Extubation of children in the operating theatre.儿童在手术室的拔管
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Basics of Extracorporeal Membrane Oxygenation.体外膜肺氧合基础。
Surg Clin North Am. 2022 Feb;102(1):23-35. doi: 10.1016/j.suc.2021.09.001.
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A new mode of mechanical ventilation: positive + negative synchronized ventilation.一种新的机械通气模式:正压+负压同步通气。
Multidiscip Respir Med. 2021 Sep 6;16(1):788. doi: 10.4081/mrm.2021.788. eCollection 2021 Jan 15.
9
Acute Kidney Injury During Extracorporeal Membrane Oxygenation: VA ECMO Versus VV ECMO.体外膜肺氧合期间的急性肾损伤:VA ECMO与VV ECMO对比
J Intensive Care Med. 2022 Jun;37(6):743-752. doi: 10.1177/08850666211035323. Epub 2021 Aug 16.
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Neonatal pneumothorax: symptoms, signs and timing of onset in the post-surfactant era.新生儿气胸:表面活性物质时代后的症状、体征和发病时间。
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