Khadayat Ramesh, Shrestha Sailesh, Gautam Tilak, Magar Sagar Rana, Bhatta Prashant
Patan Hospital Patan Academy of Health Science Lalitpur Nepal.
Clin Case Rep. 2025 Jan 6;13(1):e70064. doi: 10.1002/ccr3.70064. eCollection 2025 Jan.
Immune thrombocytopenia (ITP) is an autoimmune disorder marked by a low platelet count, leading to symptoms ranging from mild to severe bleeding. It can be triggered by various factors, including idiopathic origins, medications, malignancies, infections, and other autoimmune conditions. Though rare, ITP can also occur postvaccination. We report a case of a 3-month-old male who developed petechial rashes and mucosal bleeding following Pentavalent vaccination. This highlights the need for clinicians to recognize ITP as a potential complication of the Pentavalent vaccine. Educating parents about this rare but serious side effect is crucial.
免疫性血小板减少症(ITP)是一种自身免疫性疾病,其特征为血小板计数低,可导致从轻度到重度出血的各种症状。它可由多种因素引发,包括特发性病因、药物、恶性肿瘤、感染及其他自身免疫性疾病。虽然罕见,但ITP也可在接种疫苗后发生。我们报告一例3个月大男性,在接种五价疫苗后出现瘀点皮疹和黏膜出血。这凸显了临床医生将ITP识别为五价疫苗潜在并发症的必要性。对家长进行关于这种罕见但严重副作用的教育至关重要。