Ishino Takashi, Nakagawa Kei, Higashikawa Fumiko, Hirokane Sakura, Fujita Rikuto, Ishikawa Chie, Kawasumi Tomohiro, Takemoto Kota, Oda Takashi, Nishida Manabu, Horibe Yuichiro, Chikuie Nobuyuki, Taruya Takayuki, Hamamoto Takao, Ueda Tsutomu, Yuge Louis, Takeno Sachio
Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan.
Department of Biomechanics, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan.
Biology (Basel). 2024 Dec 6;13(12):1021. doi: 10.3390/biology13121021.
Aural rehabilitation with hearing aids can decrease the attentional requirements of cognitive resources by amplifying deteriorated-frequency sound in hearing loss patients and improving auditory discrimination ability like speech-in-noise perception. As aural rehabilitation with an intelligible-hearing sound also can be hopeful, the aim of this study was to evaluate the effectiveness of aural rehabilitation with intelligible-hearing sound for hearing loss patients. Adult native Japanese speakers (17 males and 23 females, 68.43 ± 9.23 years) with hearing thresholds exceeding 30 dB at any of the following frequencies: 125, 250, 500, 1000, 2000, 3000, 4000, 8000, 10,000, and 12,000 Hz in either ear, were recruited. on any side were recruited and underwent the Mini-Mental State Examination Japanese. We conducted a self-evaluation questionnaire for hearing problems of voice, a gap detection test, a fast speech test, a speech-in-noise test, a pure tone audiogram, and a speech perception test using a Japanese 67-S, cortical auditory-evoked fields, and magnetic mismatch negativity before and after the non-intelligible-hearing ( = 20) and intelligible-hearing ( = 20) sound therapy, which involved listening to music for one hour a day for 35 days. The better hearing ear was defined using a four-frequency pure-tone average at the thresholds of 500, 1000, 2000, and 4000 Hz. After the sound therapy, the speech-in-noise test with a signal-to-noise ratio +10 in the better hearing ear showed significant improvement ( < 0.05), and N1m-P2m amplitudes showed a significant increase in the Lt superior temporal gyrus in response to the stimulus from the better hearing ear ( < 0.05). A significant enhancement of the magnetic mismatch negativity amplitude at the Lt superior temporal gyrus was exhibited after the sound therapy ( < 0.01). Intelligible-hearing sound therapy can improve the ability of speech-in-noise perception in the better hearing ear and enhancement of central cortex response, which reflects the ability of working memory, was proved by cortical auditory-evoked fields and magnetic mismatch negativity. Intelligible-hearing sound therapy can be a valuable aural rehabilitation method for sensory neural hearing loss, the same as hearing aids.
助听器进行听觉康复可通过放大听力损失患者频率受损的声音以及提高听觉辨别能力（如噪声中的言语感知能力）来降低对认知资源的注意力需求。由于可理解听觉声音的听觉康复也可能具有前景，本研究旨在评估可理解听觉声音的听觉康复对听力损失患者的有效性。招募了双耳在以下任何频率（125、250、500、1000、2000、3000、4000、8000、10000和12000赫兹）听力阈值超过30分贝的以日语为母语的成年人（17名男性和23名女性，68.43±9.23岁）。招募了任何一侧的患者并进行了日本版简易精神状态检查表测试。在不可理解听觉（n = 20）和可理解听觉（n = 20）声音疗法前后，我们进行了语音听力问题自评问卷、间隙检测测试、快速言语测试、噪声中的言语测试、纯音听力图以及使用日本67 - S的言语感知测试、皮层听觉诱发电位和磁失配负波，声音疗法包括每天听一小时音乐，持续35天。较好听力耳通过500、1000、2000和4000赫兹阈值处的四频率纯音平均值来定义。声音疗法后，较好听力耳信噪比为 +10的噪声中的言语测试显示出显著改善（p < 0.05），并且在左颞上回，N1m - P2m振幅在对较好听力耳的刺激做出反应时显著增加（p < 0.05）。声音疗法后，左颞上回的磁失配负波振幅显著增强（p < 0.（此处原文有误，推测应为p < 0.01））。皮层听觉诱发电位和磁失配负波证明，可理解听觉声音疗法可提高较好听力耳中噪声中的言语感知能力，并增强反映工作记忆能力的中央皮层反应。可理解听觉声音疗法与助听器一样，对于感音神经性听力损失可能是一种有价值的听觉康复方法。
