Scorianz Maurizio, Scoccianti Guido, Guariento Lorenzo, Carfagni Monica, Campanacci Domenico Andrea
Orthopaedic Oncology and Reconstructive Surgery, Careggi University Hospital, 50134 Florence, Italy.
Department of Industrial Engineering, University of Florence, 50139 Florence, Italy.
Cancers (Basel). 2024 Dec 16;16(24):4185. doi: 10.3390/cancers16244185.
Joint-sparing resection of juxta-articular knee tumors is challenging. With the development of 3D printing technology, custom-made cutting guides were introduced with the aim to improve the accuracy of tumor resection margins and to shape the allograft for adequate matching in biological reconstruction. Between December 2017 and July 2023, 13 patients underwent joint-sparing juxta-articular resection of the knee for a primary bone tumor at our institution. Resection was performed using a custom-made 3D-printed titanium alloy cutting guide and reconstruction was performed using a custom-shaped allograft. The mean follow up was 50 months (min 14-max 81). The study of cutting accuracy was performed by digital examination of CT images of the resection specimen in eight patients. The average cutting error was 2.3 mm. Surgical margins were wide in all patients. Four patients developed postoperative complications that led to the removal of the allograft in one case. The average functional result according to the Musculoskeletal Tumor Society Score was 26 (min 14-max 30), and according to the Oxford Knee Score it was 44 (min 22-max 48). Custom-made titanium cutting guides resulted effective in improving the accuracy of joint-sparing juxta-articular resection of the knee and allograft matching.
保留关节的膝关节周围肿瘤切除术具有挑战性。随着3D打印技术的发展,引入了定制切割导板,旨在提高肿瘤切除边缘的准确性,并对同种异体骨进行塑形,以便在生物重建中实现充分匹配。在2017年12月至2023年7月期间,我们机构有13例患者因原发性骨肿瘤接受了保留关节的膝关节周围切除术。使用定制的3D打印钛合金切割导板进行切除,并使用定制形状的同种异体骨进行重建。平均随访时间为50个月(最短14个月 - 最长81个月)。对8例患者切除标本的CT图像进行数字检查,以研究切割精度。平均切割误差为2.3毫米。所有患者的手术切缘均为阴性。4例患者出现术后并发症,其中1例导致同种异体骨移除。根据肌肉骨骼肿瘤学会评分,平均功能结果为26分(最低14分 - 最高30分),根据牛津膝关节评分,为44分(最低22分 - 最高48分)。定制的钛切割导板在提高保留关节的膝关节周围切除术的准确性和同种异体骨匹配方面是有效的。