Savvidou Olga D, Goumenos Stavros, Trikoupis Ioannis, Kaspiris Angelos, Melissaridou Dimitra, Gavriil Panagiotis, Georgoulis Jimmy, Papagelopoulos Panayiotis J
First Department of Orthopedics, National and Kapodistrian University of Athens, Medical School, Zografou, Greece.
ATTIKON University General Hospital, Rimini 1, Chaidari, Athens, Greece.
Sarcoma. 2022 Jun 2;2022:5153924. doi: 10.1155/2022/5153924. eCollection 2022.
Parosteal osteosarcoma (PAOS) is a surface osteosarcoma. Treatment options include wide excision and endoprosthetic or allograft. However, due to the low local recurrence and metastasis rate, when it appears in the posterior surface of the distal femur, the lesion can be managed with hemicortical wide resection and biological reconstruction with hemicortical allograft. The purpose of this study is to evaluate the oncological and functional outcomes of patients with parosteal osteosarcoma (PAOS) of the posterior cortex of the distal femur who underwent biological reconstruction after hemicortical resection.
Eleven patients who underwent wide tumor resection and defect reconstruction of the posterior surface of the distal femur using hemicortical allograft were retrospectively studied. Local recurrence, metastasis, complications, and the functional outcome using the Musculoskeletal Tumor Society (MSTS) scoring system were evaluated.
The average postoperative follow-up period was 53.64 months (range, 30 to 84 months). At the latest follow-up, all patients had no evidence of disease without metastases. One patient with local recurrence underwent revision surgery with fibula autograft reconstruction. The mean MSTS score was 93.45 ± 3.56.
Treatment of patients with PAOS of the posterior aspect of the distal femur with hemicortical resection and allograft reconstruction has satisfactory oncological and functional outcome and low complication rates.
骨旁骨肉瘤（PAOS）是一种表面骨肉瘤。治疗选择包括广泛切除及使用人工关节假体或同种异体骨移植。然而，由于局部复发和转移率较低，当病变出现在股骨远端后表面时，可采用半皮质广泛切除并用半皮质同种异体骨进行生物重建来处理。本研究的目的是评估股骨远端后皮质骨旁骨肉瘤（PAOS）患者在半皮质切除后进行生物重建的肿瘤学和功能结局。
回顾性研究11例采用半皮质同种异体骨对股骨远端后表面进行广泛肿瘤切除及缺损重建的患者。评估局部复发、转移、并发症以及使用肌肉骨骼肿瘤学会（MSTS）评分系统的功能结局。
术后平均随访期为53.64个月（范围30至84个月）。在最近一次随访时，所有患者均无疾病且无转移证据。1例局部复发患者接受了腓骨自体骨移植重建翻修手术。MSTS平均评分为93.45±3.56。
对股骨远端后侧PAOS患者采用半皮质切除及同种异体骨移植重建治疗，具有令人满意的肿瘤学和功能结局，且并发症发生率低。
