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亚裔美国人的结肠癌发病率:2017 - 2021年流行病学分析

Colon Cancer Rates Among Asian Americans: A 2017-2021 Epidemiological Analysis.

作者信息

Do Candice, Lee Wei-Chen, Doan Christopher Huy D, Xie Cathy, Campbell Kendall M

机构信息

John Sealy School of Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.

Department of Family Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.

出版信息

Cancers (Basel). 2024 Dec 20;16(24):4254. doi: 10.3390/cancers16244254.

Abstract

Colon cancer (CC) is a significant public health concern. With Asian Americans (AAs) representing a rapidly growing demographic in the United States, our study examined CC prevalence among AAs. The study merged the 2017-2021 Medical Expenditure Panel Survey and County Health Ranking. Our analysis calculated age-adjusted CC rates and examined its prevalence across states. Regression analyses were conducted to study county-level risk factors of CC. The CC age-adjusted rate among AAs increased by five-fold, from 155 per 100,000 in 2017 to 753 per 100,000 in 2021. State-level disparities revealed the highest CC prevalence in Arkansas, Rhode Island, and New Hampshire. Not speaking other languages and having insurance were significantly associated with higher CC rates, suggesting barriers to preventions and greater use of screening ( < 0.05). County-level analysis identified lower CC prevalence in regions with a greater socioeconomic advantage ( < 0.05). Socioeconomic advantage seemed to facilitate higher screening rates, which then translated into higher CC rates. Our findings underscore the need for early preventions to address rising CC rates among AAs. Future research should also explore geographic factors to better understand the disparities in CC risk.

摘要

结肠癌(CC)是一个重大的公共卫生问题。随着亚裔美国人(AAs)在美国人口中所占比例迅速增长,我们的研究调查了亚裔美国人中的结肠癌患病率。该研究将2017 - 2021年医疗支出面板调查和县级卫生排名进行了合并。我们的分析计算了年龄调整后的结肠癌发病率,并考察了其在各州的患病率。进行了回归分析以研究县级结肠癌的风险因素。亚裔美国人中结肠癌年龄调整后的发病率增长了五倍,从2017年的每10万人155例增至2021年的每10万人753例。州级差异显示,阿肯色州、罗德岛州和新罕布什尔州的结肠癌患病率最高。不会说其他语言和拥有保险与较高的结肠癌发病率显著相关,这表明预防存在障碍,且筛查使用率更高(P < 0.05)。县级分析发现,社会经济优势较大的地区结肠癌患病率较低(P < 0.05)。社会经济优势似乎促进了更高的筛查率,进而转化为更高的结肠癌发病率。我们的研究结果强调了早期预防以应对亚裔美国人中不断上升的结肠癌发病率的必要性。未来的研究还应探索地理因素,以更好地理解结肠癌风险的差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85a0/11675008/a70c8f079048/cancers-16-04254-g001.jpg

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