GI Section, VA San Diego Healthcare System, Department of Gastroenterology, University of California San Diego, 3350 La Jolla Village Drive, MC 111D, San Diego, CA 92161, USA.
Hematol Oncol Clin North Am. 2022 Jun;36(3):393-414. doi: 10.1016/j.hoc.2022.02.001. Epub 2022 Apr 30.
Colorectal cancer (CRC) is the second-leading cause of cancer death in the United States. Screening reduces CRC incidence and mortality. 2021 US Preventive Service Task Force (USPSTF) guidelines and available evidence support routine screening from ages 45 to 75, and individualized consideration of screening ages 76 to 85. USPSTF guidelines recommend annual guaiac fecal occult blood testing, annual fecal immunochemical testing (FIT), annual to every 3-year multitarget stool DNA-FIT, every 5-year sigmoidoscopy, every 10-year sigmoidoscopy with annual FIT, every 5-year computed tomographic colonography, and every 10-year colonoscopy as options for screening. The "best test is the one that gets done."
结直肠癌(CRC)是美国第二大癌症死亡原因。筛查可降低 CRC 的发病率和死亡率。2021 年美国预防服务工作组(USPSTF)指南和现有证据支持 45 岁至 75 岁的常规筛查,以及 76 岁至 85 岁的个体化筛查考虑。USPSTF 指南建议每年进行愈创木脂粪便潜血检测、每年进行粪便免疫化学检测(FIT)、每年至每 3 年进行多靶点粪便 DNA-FIT、每 5 年进行乙状结肠镜检查、每 10 年进行乙状结肠镜检查加 FIT、每 5 年进行计算机断层结肠成像术和每 10 年进行结肠镜检查作为筛查的选择。“最好的检查是能完成的检查。”