Förster Carola Y
Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, Cerebrovascular Sciences and Neuromodulation, Würzburg University, 97080 Würzburg, Germany.
Biomolecules. 2024 Nov 26;14(12):1511. doi: 10.3390/biom14121511.
A new therapeutic approach, known as neuromodulation therapy-which encompasses a variety of interventional techniques meant to alter the nervous system in order to achieve therapeutic effects-has emerged in recent years as a result of advancements in neuroscience. Currently used methods for neuromodulation include direct and indirect approaches, as well as invasive and non-invasive interventions. For instance, the two primary methods of stimulating the vagus nerve (VN) are invasive VN stimulation (iVNS) and transcutaneous VN stimulation (tVNS). Since the latter is non-invasive, basic, clinical, and translational studies have focused on transcutaneous auricular VN stimulation (taVNS), the primary tVNS therapy, because of its advantages over iVNS, including ease of use, greater accessibility, and a lower side effect profile. taVNS is currently used as a novel neuromodulatory application to treat cardiovascular, mental, and autoimmune diseases. Future applications of this non-invasive neuromodulation technology to conditions like atrial fibrillation (AF) or ischemic stroke are highly likely due to its advancement.
一种被称为神经调节疗法的新治疗方法近年来随着神经科学的进步而出现，这种疗法包括多种旨在改变神经系统以达到治疗效果的介入技术。目前用于神经调节的方法包括直接和间接方法，以及侵入性和非侵入性干预措施。例如，刺激迷走神经（VN）的两种主要方法是侵入性迷走神经刺激（iVNS）和经皮迷走神经刺激（tVNS）。由于后者是非侵入性的，基础、临床和转化研究都集中在经皮耳迷走神经刺激（taVNS）上，它是主要的tVNS疗法，因为它比iVNS具有优势，包括使用方便、更容易获得以及副作用较小。taVNS目前被用作一种新型神经调节应用来治疗心血管疾病、精神疾病和自身免疫性疾病。由于其不断发展，这种非侵入性神经调节技术未来极有可能应用于心房颤动（AF）或缺血性中风等病症。
