Sun Hui, Zhang Jiajia, Zhu Junjie, Xu Boya, Gao Yinyan, Zhang Dexing, Wu Irene X Y, Hu Yanhong Jessika, Deng Shuzhen
Baoshan Center for Disease Control and Prevention, Shanghai 200000, China.
Xiangya School of Public Health, Central South University, Changsha 410000, China.
Antibiotics (Basel). 2024 Dec 6;13(12):1189. doi: 10.3390/antibiotics13121189.
The misuse of antibiotics in both humans and food-producing animals poses significant risks to human health and contributes to the rise of antibiotic resistance. Raising public awareness is crucial to managing antibiotic resistance, particularly among university students, as they represent a future force in tackling this global issue. A cross-sectional study was conducted from July 2022 to May 2024 in seven cities in Southern and Central China to assess university students' knowledge, attitude, and practice regarding antibiotic use in humans and food-producing animals. Binary logistic regression was used to identify associated factors. A total of 6357 students from 72 universities participated. Less than half of the students answered the knowledge items appropriately. Only 21.47% to 29.98% had a proper understanding of basic antibiotic concepts and their use in humans and food-producing animals. Respectively, 21.49% and 28.50% students paid attention to antibiotic content in food from food-producing animals and refused to buy food containing antibiotics. Factors associated with higher knowledge, attitude, and practice total scores included being male, being of older age, having a postgraduate education, majoring in the medical science discipline, studying at a double-first-class university, having a higher family monthly income, having parents in the medical area, and using antibiotics in the past year ( < 0.001). Given students' insufficient knowledge-particularly in identifying antibiotics and understanding their functions-and inappropriate practices related to purchasing food from food-producing animals, targeted education programs are suggested. These programs should address the fundamental concepts of antibiotic use in both humans and food-producing animals while providing practical guidance on individual behaviors to help mitigate antibiotic resistance.
人类和食用动物中抗生素的滥用对人类健康构成重大风险，并导致抗生素耐药性的上升。提高公众意识对于控制抗生素耐药性至关重要，尤其是在大学生中，因为他们是应对这一全球问题的未来力量。2022年7月至2024年5月在中国南部和中部的七个城市进行了一项横断面研究，以评估大学生对人类和食用动物使用抗生素的知识、态度和行为。采用二元逻辑回归分析相关因素。共有来自72所大学的6357名学生参与。不到一半的学生正确回答了知识问题。只有21.47%至29.98%的学生对基本抗生素概念及其在人类和食用动物中的使用有正确的理解。分别有21.49%和28.50%的学生关注食用动物食品中的抗生素含量，并拒绝购买含有抗生素的食品。与知识、态度和行为总分较高相关的因素包括男性、年龄较大、拥有研究生学历、医学专业、就读于双一流大学、家庭月收入较高、父母从事医疗行业以及在过去一年中使用过抗生素（<0.001）。鉴于学生知识不足——尤其是在识别抗生素和理解其功能方面——以及在购买食用动物食品方面的不当行为，建议开展有针对性的教育项目。这些项目应涉及人类和食用动物使用抗生素方面的基本概念，同时为个人行为提供实际指导，以帮助减轻抗生素耐药性。
