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1
Giving Up the Guidelines: A Qualitative Evaluation of Disrupted Prescribing of Opioid Substitution Therapy in a Rural UK County During and Following the COVID-19 Pandemic.放弃指南:对英国一个乡村郡在新冠疫情期间及之后阿片类药物替代疗法中断处方的定性评估
Int J Environ Res Public Health. 2024 Nov 30;21(12):1605. doi: 10.3390/ijerph21121605.
2
Response of tertiary addictions services to opioid dependence during the COVID-19 pandemic.在 COVID-19 大流行期间,三级成瘾服务机构对阿片类药物依赖的反应。
Ir J Psychol Med. 2021 Dec;38(4):301-306. doi: 10.1017/ipm.2021.8. Epub 2021 Feb 4.
3
Understanding and learning from rural drug service adaptations to opioid substitution therapy during the COVID-19 pandemic: the What C-OST? study.理解和学习农村药物服务在 COVID-19 大流行期间对阿片类药物替代疗法的适应:What C-OST?研究。
Front Public Health. 2023 Nov 30;11:1240402. doi: 10.3389/fpubh.2023.1240402. eCollection 2023.
4
A national model of remote care for assessing and providing opioid agonist treatment during the COVID-19 pandemic: a report.全国远程医疗模式评估及在 COVID-19 大流行期间提供阿片类激动剂治疗:报告。
Harm Reduct J. 2020 Jul 17;17(1):49. doi: 10.1186/s12954-020-00394-z.
5
Supervised dosing with a long-acting opioid medication in the management of opioid dependence.在阿片类药物依赖管理中使用长效阿片类药物进行监督给药。
Cochrane Database Syst Rev. 2017 Apr 27;4(4):CD011983. doi: 10.1002/14651858.CD011983.pub2.
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The impact of COVID-19 on healthcare delivery for people who use opioids: a scoping review.COVID-19 对使用阿片类药物人群的医疗服务提供的影响:范围综述。
Subst Abuse Treat Prev Policy. 2021 Aug 9;16(1):60. doi: 10.1186/s13011-021-00395-6.
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Living Under Coronavirus and Injecting Drugs in Bristol (LUCID-B): A qualitative study of experiences of COVID-19 among people who inject drugs.布里斯托新冠肺炎和吸毒人群研究(LUCID-B):一项关于吸毒人群感染新冠经历的定性研究。
Int J Drug Policy. 2021 Dec;98:103391. doi: 10.1016/j.drugpo.2021.103391. Epub 2021 Jul 20.
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Changes in Opioid Agonist Treatment Practice in Germany during the COVID-19 Pandemic: What Have Physicians Done, and What Would They Like to Keep Doing?新冠疫情期间德国阿片类激动剂治疗实践的变化:医生们做了什么,他们希望继续做什么?
Eur Addict Res. 2023;29(5):323-332. doi: 10.1159/000531593. Epub 2023 Aug 9.
9
Feasibility and Short-Term Effects of Low-Threshold Opioid Substitution Treatment during the COVID-19 Pandemic in Hamburg, Germany.德国汉堡在新冠大流行期间实施低门槛阿片类物质替代治疗的可行性和短期效果。
Eur Addict Res. 2023;29(1):44-51. doi: 10.1159/000527826. Epub 2022 Dec 19.
10
Health screening clinic to reduce absenteeism and presenteeism among NHS Staff: eTHOS a pilot RCT.健康筛查门诊减少 NHS 员工旷工和出勤主义:eTHOS 一项试点 RCT。
Health Soc Care Deliv Res. 2024 Aug;12(23):1-105. doi: 10.3310/KDST3869.

本文引用的文献

1
Understanding and learning from rural drug service adaptations to opioid substitution therapy during the COVID-19 pandemic: the What C-OST? study.理解和学习农村药物服务在 COVID-19 大流行期间对阿片类药物替代疗法的适应:What C-OST?研究。
Front Public Health. 2023 Nov 30;11:1240402. doi: 10.3389/fpubh.2023.1240402. eCollection 2023.
2
Superiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial.每月一次缓释丁丙诺啡与每日标准护理药物相比的优越性和成本效益:一项实用、平行组、开放标签、多中心、随机、对照的3期试验。
EClinicalMedicine. 2023 Nov 17;66:102311. doi: 10.1016/j.eclinm.2023.102311. eCollection 2023 Dec.
3
What can we learn from COVID-19 to improve opioid treatment? Expert providers respond.从 COVID-19 中我们可以学到什么来改善阿片类药物治疗?专家提供了回应。
J Subst Use Addict Treat. 2023 Nov;154:209157. doi: 10.1016/j.josat.2023.209157. Epub 2023 Aug 29.
4
Changes to methadone maintenance therapy in the United States, Canada, and Australia during the COVID-19 pandemic: A narrative review.新冠疫情期间美国、加拿大和澳大利亚美沙酮维持治疗的变化:叙述性综述。
J Subst Use Addict Treat. 2023 Sep;152:209086. doi: 10.1016/j.josat.2023.209086. Epub 2023 Jun 1.
5
Patients' perceptions of self-administered dosing to opioid agonist treatment and other changes during the COVID-19 pandemic: a qualitative study.患者对 COVID-19 大流行期间阿片类激动剂治疗自我给药和其他变化的看法:一项定性研究。
BMJ Open. 2023 Mar 21;13(3):e069857. doi: 10.1136/bmjopen-2022-069857.
6
"You'll come in and dose even in a global pandemic": A qualitative study of adaptive opioid agonist treatment provision during the COVID-19 pandemic.“即使在全球大流行期间,我们也会上门给药”:一项关于 COVID-19 大流行期间适应性阿片类激动剂治疗提供情况的定性研究。
Int J Drug Policy. 2023 Apr;114:103998. doi: 10.1016/j.drugpo.2023.103998. Epub 2023 Mar 6.
7
Synthesising evidence of the effects of COVID-19 regulatory changes on methadone treatment for opioid use disorder: implications for policy.综合 COVID-19 监管变化对阿片类药物使用障碍美沙酮治疗效果的证据:对政策的影响。
Lancet Public Health. 2023 Mar;8(3):e238-e246. doi: 10.1016/S2468-2667(23)00023-3.
8
Should I Stay or Should I Go? A Qualitative Exploration of Stigma and Other Factors Influencing Opioid Agonist Treatment Journeys.我该留下还是离开?定性探讨影响阿片类激动剂治疗旅程的污名化和其他因素。
Int J Environ Res Public Health. 2023 Jan 14;20(2):1526. doi: 10.3390/ijerph20021526.
9
Key implementation factors in telemedicine-delivered medications for opioid use disorder: a scoping review informed by normalisation process theory.远程医疗提供阿片类药物使用障碍药物的关键实施因素:基于常规过程理论的范围综述。
Lancet Psychiatry. 2023 Jan;10(1):50-64. doi: 10.1016/S2215-0366(22)00374-1.
10
Lessons from the COVID-19 pandemic for substance misuse services: findings from a peer-led study.从 COVID-19 大流行中学到的关于药物滥用服务的经验教训:一项同行主导研究的结果。
Harm Reduct J. 2022 Dec 12;19(1):140. doi: 10.1186/s12954-022-00713-6.

放弃指南:对英国一个乡村郡在新冠疫情期间及之后阿片类药物替代疗法中断处方的定性评估

Giving Up the Guidelines: A Qualitative Evaluation of Disrupted Prescribing of Opioid Substitution Therapy in a Rural UK County During and Following the COVID-19 Pandemic.

作者信息

Lewington Tim, Burch Deanne, Petitjean Georges

机构信息

Research & Innovation Department, Midlands Partnership University NHS Foundation Trust, St. George's Hospital, Stafford ST16 3AG, UK.

Inclusion, Midlands Partnership University NHS Foundation Trust, St. George's Hospital, Stafford ST16 3AG, UK.

出版信息

Int J Environ Res Public Health. 2024 Nov 30;21(12):1605. doi: 10.3390/ijerph21121605.

DOI:10.3390/ijerph21121605
PMID:39767446
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11675789/
Abstract

The COVID-19 pandemic had wide impacts and repercussions for the NHS in the UK beyond the acute medical sector. This qualitative study evaluates the experience of medical (4) and non-medical prescribers (7) plus other staff (2 recovery workers; 2 community pharmacists) involved in opioid substitution therapy (OST) in a southern English county during and following the COVID-19 pandemic. Remote contact and a shift to predominantly weekly OST pick-up were anxiety-producing for clinicians, especially during the first lockdown. Widespread negative consequences were anticipated, such as a rise in fatal overdoses, which largely failed to materialise. Some diversion of medication was noted as were negative mental health consequences of enforced social isolation. Following a hiatus, psychosocial therapies transitioned to fully digital and subsequently hybrid delivery before returning to in-person group work towards the close of the pandemic. Changing power dynamics between clinicians and those accessing OST services were reported particularly around the re-introduction of daily supervised consumption and associated surveillance. Implications for future OST service delivery and national clinical guidance are suggested by way of conclusions.

摘要

新冠疫情对英国国民医疗服务体系(NHS)产生了广泛影响,其影响范围超出了急性医疗领域。这项定性研究评估了在新冠疫情期间及之后,英国南部一个郡参与阿片类药物替代疗法(OST)的医学处方者(4名)、非医学处方者(7名)以及其他工作人员(2名康复工作者;2名社区药剂师)的经历。远程联系以及主要改为每周领取一次OST药物,给临床医生带来了焦虑,尤其是在首次封锁期间。人们预计会出现广泛的负面后果,比如致命过量用药情况增加,但这些情况大多并未出现。发现了一些药物转移现象,以及强制社会隔离对心理健康产生的负面影响。经过一段时间的中断后,心理社会治疗过渡到完全数字化,随后又采用混合式提供方式,在疫情接近尾声时恢复面对面小组治疗。据报告,临床医生与接受OST服务者之间的权力动态发生了变化,尤其是在重新引入每日监督服药及相关监测方面。结论部分提出了对未来OST服务提供及国家临床指南的启示。