Giannattasio Antonietta, Maglione Marco, Di Nardo Giangiacomo, Di Marco Giovanni Maria, Lauretta Daria, Carrella Maria Chiara, Furlan Daniela, Savoia Fabio, Tipo Vincenzo
Pediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
Pediatric Cardiology Unit, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
Children (Basel). 2024 Nov 23;11(12):1414. doi: 10.3390/children11121414.
Acute fulminant myocarditis is a rare event in children, accounting for about 10% of all cases of acute myocarditis. Its lack of specific onset patterns and unpredictable evolution make diagnosis and prompt treatment challenging. We observed six cases of fulminant myocarditis admitted to our Pediatric Emergency Unit (Campania region, Sothern Italy) within a very short timeframe (50 days, from July to September 2024). Three of them died, and two are still under treatment in a Pediatric Cardiologic Intensive Care Unit in critical condition. In only one case, cardiac function improved. The described cases were not geographically linked, belonging to different areas of Southern Italy. No common etiological agent was found. Given the relatively low incidence of the condition, the occurrence of six pediatric myocarditis within approximately two months should be considered exceptional. Careful monitoring of further cases in the next few months should be warranted.
急性暴发性心肌炎在儿童中是一种罕见疾病，约占急性心肌炎病例总数的10%。其缺乏特定的发病模式且演变不可预测，这使得诊断和及时治疗具有挑战性。我们观察到在很短的时间内（2024年7月至9月的50天内），有6例暴发性心肌炎患儿入住我们的儿科急诊科（意大利南部坎帕尼亚地区）。其中3例死亡，2例仍在儿科心脏病重症监护病房接受治疗，病情危急。只有1例心脏功能有所改善。所描述的病例在地理上并无关联，来自意大利南部的不同地区。未发现共同的病原体。鉴于该病发病率相对较低，在大约两个月内出现6例儿童心肌炎病例应被视为异常情况。接下来几个月应对更多病例进行密切监测。
