Angolkar Yashaswini S, Kulkarni Sadanand, Yavagal Chandrashekar M, Yavagal Puja C, Bhosle Umesh, Patil Viplavi Chavan, Almalki Sultan Abdulrahman, Gowdar Inderjit Murugendrappa, Gufran Khalid
Department of Pediatric Dentistry, Maratha Mandal's Nathajirao G. Halgekar Institute of Dental Sciences & Research Centre, Belgaum 590019, India.
Department of Pedodontics and Preventive Dentistry, Bapuji Dental College and Hospital, Davanagere 577004, India.
Children (Basel). 2024 Dec 12;11(12):1511. doi: 10.3390/children11121511.
This study aimed to assess the effectiveness of laser photobiomodulation (PBM) in reducing postoperative pain following single-visit endodontic treatment in children aged 5-9 years.
Forty children aged 5-9 years with acute irreversible pulpitis in deciduous molars requiring single-visit pulpectomy were included in the study. Pulpectomy was performed according to a standard endodontic protocol. The participants were randomly allocated to two groups: group A received laser photobiomodulation using an 810 nm diode laser applied to the periapical area of the treated tooth postoperatively, and group B received blue light LED, applied at similar points to the control teeth. This was a placebo intervention. Pain scores were measured using a 10-point Visual Analog Scale (VAS) at 4, 12, 24, and 48 h post-treatment. The Friedman test was used to compare the VAS scores within groups over time, and the Mann-Whitney U-test was used to compare the VAS scores between the two groups. The significance level was fixed at < 0.05.
The mean VAS scores were significantly lower in the PBM group compared to the placebo group at the 4th h, 12th h, and 24th h post-treatment ( ≤ 0.05). The pain levels remained stable over time in the PBM group, with no significant difference in pain scores from 4 h to 48 h ( = 0.57). In the placebo group, the pain gradually decreased from the 4th h to the 48th h, with a significant reduction in pain observed between the 12th h and 48th h ( = 0.05).
Laser photobiomodulation (PBM) was found to be effective in reducing postoperative pain following single-visit endodontic treatment in children. This non-invasive approach could offer a valuable alternative for pain management in pediatric endodontics, particularly given its effectiveness without the need for systemic medications.
本研究旨在评估激光光生物调节（PBM）对5至9岁儿童单次就诊根管治疗术后疼痛的缓解效果。
本研究纳入了40名年龄在5至9岁、患有急性不可逆性牙髓炎且需要进行单次就诊牙髓摘除术的乳牙列儿童。牙髓摘除术按照标准的根管治疗方案进行。参与者被随机分为两组：A组在术后使用810nm二极管激光对治疗牙齿的根尖周区域进行激光光生物调节，B组在对照牙齿的相同部位使用蓝光发光二极管，此为安慰剂干预。在治疗后4小时、12小时、24小时和48小时，使用10分视觉模拟量表（VAS）测量疼痛评分。采用Friedman检验比较组内不同时间点的VAS评分，采用Mann-Whitney U检验比较两组之间的VAS评分。显著性水平设定为<0.05。
与安慰剂组相比，PBM组在治疗后第4小时、第12小时和第24小时的平均VAS评分显著更低（≤0.05）。PBM组的疼痛水平随时间保持稳定，从4小时到48小时疼痛评分无显著差异（=0.57）。在安慰剂组中，疼痛从第4小时到第48小时逐渐减轻，在第12小时和第48小时之间观察到疼痛显著减轻（=0.05）。
发现激光光生物调节（PBM）对减轻儿童单次就诊根管治疗术后疼痛有效。这种非侵入性方法可为儿童牙髓病学的疼痛管理提供有价值的替代方案，特别是考虑到其有效性且无需全身用药。
