Méndez-Balbuena Ignacio, Betancourt-Navarrete Brenda Lesly, Hermosillo-Abundis Ana Cristina, Flores Amira, Rebolledo-Herrera Lucio Fidel, Lemuz-López Rafael, Huidobro Nayeli, Meza-Andrade Roberto, Pelayo-González Héctor Juan, Bonilla-Sánchez María Del Rosario, López-Cortes Vicente Arturo, García-Flores Marco Antonio
Facultad de Psicología, Benemérita Universidad Autónoma de Puebla, Puebla 72000, Mexico.
Instituto de Fisiología, Benemérita Universidad Autónoma de Puebla, Puebla 72000, Mexico.
Bioengineering (Basel). 2024 Nov 25;11(12):1187. doi: 10.3390/bioengineering11121187.
Traumatic brain injury (TBI), resulting from external forces, is a leading cause of disability and death, often leading to cognitive deficits that affect attention, concentration, speech and language, learning and memory, reasoning, planning, and problem-solving. Given the diverse mechanisms underlying TBI symptoms, it is essential to characterize its neurophysiological and neuropsychological effects. To address this, we employed weighted coherence (WC) analysis in patients performing the Halstead-Reitan categorization task, alongside a control group of eight healthy individuals. Our findings indicate a significant decrease in WC within the theta and delta bands in the temporal regions during cognitive tasks in the TBI group compared to controls. Additionally, we observed a significant increase in WC in the beta and gamma bands in the parietal region during both rest and cognitive tasks in the TBI group, relative to the control group. Furthermore, there was a strong correlation between WC and task performance scores in the temporal regions.
创伤性脑损伤（TBI）由外力导致，是残疾和死亡的主要原因，常引发影响注意力、专注力、言语和语言、学习与记忆、推理、规划及问题解决能力的认知缺陷。鉴于TBI症状背后存在多种机制，表征其神经生理和神经心理效应至关重要。为解决这一问题，我们对执行哈尔斯特德-雷坦分类任务的患者以及由八名健康个体组成的对照组进行了加权相干（WC）分析。我们的研究结果表明，与对照组相比，TBI组在认知任务期间颞区的θ波和δ波频段内WC显著降低。此外，相对于对照组，我们观察到TBI组在静息和认知任务期间顶叶区域的β波和γ波频段内WC显著增加。此外，颞区的WC与任务表现得分之间存在强相关性。
