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上颌骨萎缩患者种植牙的长期成功:一项使用羟基磷灰石和富含白细胞的纤维蛋白的3年病例系列研究

Long-Term Success of Dental Implants in Atrophic Maxillae: A 3-Year Case Series Using Hydroxyapatite and L-PRF.

作者信息

Alves Marco Andre Lomba, Both Jakson, Mourão Carlos Fernando, Ghiraldini Bruna, Bezerra Fabio, Granjeiro Jose Mauro, Sartoretto Suelen Cristina, Calasans-Maia Monica Diuana

机构信息

Post-Graduation Program in Dentistry, Fluminense Federal University, Niteroi 24220-140, Brazil.

Independent Researcher, Dois Vizinhos 85660-000, Brazil.

出版信息

Bioengineering (Basel). 2024 Nov 28;11(12):1207. doi: 10.3390/bioengineering11121207.

Abstract

Dental implants are essential for the prosthetic rehabilitation of edentulous patients, requiring adequate bone volume and density for osseointegration and load support. The posterior region of the maxilla, commonly deficient in bone quality and quantity, represents a clinical challenge. This case series reports an analysis involving 69 dental implants in the atrophic maxilla of nine patients. The procedures adopted combined alloplastic hydroxyapatite grafting and leukocyte platelet-rich fibrin (L-PRF) applied to the alveolar ridge and maxillary sinus lift. With an average follow up of three years after the installation of the prostheses, an implant success rate of 98.5% was observed, showing integration and functional stability. The strategy of combining hydroxyapatite with L-PRF proved to be effective in increasing bone volume and promoting osseointegration. These findings indicate that the technique and biomaterials are viable for rehabilitating atrophic maxillae in the posterior region, offering long-lasting clinical results and a high success rate.

摘要

牙种植体对于无牙患者的修复性康复至关重要,需要足够的骨量和骨密度以实现骨结合和负荷支持。上颌后部区域通常在骨质量和骨量方面存在不足,这是一个临床挑战。本病例系列报告了对9例患者萎缩上颌骨中69颗牙种植体的分析。所采用的手术结合了异体羟基磷灰石移植和应用于牙槽嵴及上颌窦提升的富白细胞血小板纤维蛋白(L-PRF)。在安装假体后平均随访三年,观察到种植体成功率为98.5%,显示出骨结合和功能稳定性。将羟基磷灰石与L-PRF相结合的策略被证明在增加骨量和促进骨结合方面是有效的。这些发现表明,该技术和生物材料对于修复上颌后部的萎缩性上颌骨是可行的,可提供持久的临床效果和高成功率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4189/11673170/dc8cffa79804/bioengineering-11-01207-g001.jpg

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