Udawant Tanuja, Thorat Prajkta, Thapa Payal, Patel Manali, Shekhawat Saroj, Patel Roshni, Sudhir Ankit, Hudka Om, Pulidindi Indra Neel, Deokar Archana
Modern College of Arts, Science, and Commerce, Pune 411005, India.
Department of Life Sciences, School of Science, Gujarat State Fertilizers and Chemicals University, Vadodara 391750, India.
Bioengineering (Basel). 2024 Dec 5;11(12):1234. doi: 10.3390/bioengineering11121234.
A green and cost-effective sonochemical synthetic method was followed for coating silver-modified copper oxide (Ag-CuO) nanoparticles (NPs) on disposable surgical mask. The NP-coated masks were systematically characterized using XRD and FT-IR for understanding the structural and surface functionalities. In addition, the field emission scanning electron microscopy (FE-SEM) analysis showed the homogeneous coating of Ag-CuO NPs over the mask fibers. The average particle size of Ag-CuO was found to be ~70 nm. The NP-coated masks are useful to combat a broad range of bacterial species by taking the unique advantage of the synergistic effect of Ag and metal oxide (CuO and ZnO) NPs for the generation of reactive oxygen species (ROS). Zone of inhibition (ZoI) studies demonstrated antibacterial activity against both Gram-positive and Gram-negative bacteria, probably due to the elevated production of ROS by the defect structure of the Ag-modified metal oxide NPs. The material was found to be effective against both airborne and soil-borne bacteria. We repeat that this paper deals only with the killing effect of the nanoparticles (Ag-modified CuO) on bacteria, and no studies on viral species are performed.
采用一种绿色且经济高效的声化学合成方法,将银改性氧化铜(Ag-CuO)纳米颗粒(NPs)涂覆在一次性外科口罩上。使用X射线衍射(XRD)和傅里叶变换红外光谱(FT-IR)对涂覆有纳米颗粒的口罩进行系统表征,以了解其结构和表面官能团。此外,场发射扫描电子显微镜(FE-SEM)分析表明Ag-CuO纳米颗粒均匀地涂覆在口罩纤维上。发现Ag-CuO的平均粒径约为70纳米。涂覆有纳米颗粒的口罩利用Ag与金属氧化物(CuO和ZnO)纳米颗粒协同作用产生活性氧(ROS)的独特优势,可有效对抗多种细菌。抑菌圈(ZoI)研究表明,该口罩对革兰氏阳性菌和革兰氏阴性菌均具有抗菌活性,这可能是由于Ag改性金属氧化物纳米颗粒的缺陷结构导致ROS产量增加所致。研究发现该材料对空气传播细菌和土壤传播细菌均有效。我们重申,本文仅涉及纳米颗粒(Ag改性CuO)对细菌的杀灭作用,未对病毒进行研究。