Rosa Maria Silvia, Dell'Era Valeria, Campagnoli Massimo, Campini Silvia, Barozza Ottavia, Borello Giovanni, Garzaro Massimiliano, Aluffi Valletti Paolo
ENT Division, Health Science Department, School of Medicine, 28100 Novara, Italy.
Department of Otorhinolaryngology, Ss. Trinità Hospital, 28021 Borgomanero, Italy.
J Clin Med. 2024 Dec 12;13(24):7576. doi: 10.3390/jcm13247576.
Voice alteration is a recognized complication of thyroid surgery, impacting the quality of life and communication for affected individuals. In this prospective observational study, the Acoustic Voice Quality Index (AVQI) was employed to assess vocal outcomes after thyroidectomy. Between February 2018 and August 2022, 224 patients underwent Thyroid surgery in our department, of which 74 with differentiated thyroid carcinoma (DTC) were enrolled in accordance with the inclusion criteria. Endoscopic findings and AVQI scores were evaluated before and after surgery (voice analysis was conducted using the Praat software program version 6.0.33). Vocal fold impairment was present in 6.76% of patients after surgery (T1), with full recovery within 3 months. During preadmission evaluation, an AVQI score > 2.35 indicating hoarseness was present in 37 patients (despite normal vocal cord motility). Of these, 25 (67.57%), 26 (70.27%), and 24 (17.76%) maintained this trend at T1, T2, and T3, respectively. No significant variation in mean AVQI values was observed based on gender, age, and central neck dissection. AVQI values did not show significant variations comparing pre- and postoperative values. Thyroid surgery for DTC performed by experienced surgeons does not seem to impact significantly on patients' voice quality.
嗓音改变是甲状腺手术公认的并发症，会影响患者的生活质量和交流。在这项前瞻性观察研究中，采用声学嗓音质量指数（AVQI）评估甲状腺切除术后的嗓音结果。2018年2月至2022年8月期间，我科有224例患者接受了甲状腺手术，其中74例分化型甲状腺癌（DTC）患者符合纳入标准。在手术前后评估内镜检查结果和AVQI评分（使用Praat软件程序版本6.0.33进行嗓音分析）。术后（T1）6.76%的患者存在声带损伤，3个月内完全恢复。入院前评估时，37例患者AVQI评分>2.35提示声音嘶哑（尽管声带运动正常）。其中，分别有25例（67.57%）、26例（70.27%）和24例（17.76%）在T1、T2和T3时保持这一趋势。根据性别、年龄和中央区颈清扫情况，未观察到平均AVQI值有显著差异。术前和术后的AVQI值比较也未显示出显著差异。经验丰富的外科医生进行的DTC甲状腺手术似乎对患者的嗓音质量没有显著影响。
