Mazzitelli Maria, Sartori Maria Teresa, Scaglione Vincenzo, Lucente Fabrizio, Gerosa Gino, Leonardi Andrea, Castagliuolo Ignazio, Pergola Valeria, Simioni Paolo, Cattelan Annamaria
Infectious and Tropical Diseases Unit, Padua University Hospital, 35128 Padua, Italy.
Department of Medicine-DIMED, Padua University Hospital, 35128 Padua, Italy.
Medicina (Kaunas). 2024 Dec 2;60(12):1991. doi: 10.3390/medicina60121991.
Almost 25 years have now passed since the first identification of (). It can cause infections both in immunocompetent and immunocompromised hosts. However, it has been rarely described as an aetiology of infectious endocarditis. We herein report the case of a 75-year-old Italian gentleman who was admitted for shortness of breath, asthenia, weight loss, and an episode of loss of consciousness and who was subsequently diagnosed with endocarditis (the first reported in Italy). He was, therefore, treated with ceftriaxone for six weeks and underwent cardiac surgery. We performed a literature review on endocarditis cases and found 12 other reported cases. Demographics, clinical presentation, prognostic factors, treatment, and outcomes were summarized. Despite anecdotic cases being reported, endocarditis can occur and should be promptly and properly identified using accurate diagnostic methods. Continued research into its epidemiology, pathogenesis, antimicrobial resistance, and host interactions is essential for enhancing our knowledge and improving clinical management strategies.
自首次鉴定出（）至今已过去近25年。它可在免疫功能正常和免疫功能低下的宿主中引起感染。然而，它很少被描述为感染性心内膜炎的病因。我们在此报告一例75岁意大利男性病例，该患者因气短、乏力、体重减轻和一次意识丧失发作入院，随后被诊断为（）性心内膜炎（意大利首例报告）。因此，他接受了六周的头孢曲松治疗并接受了心脏手术。我们对（）性心内膜炎病例进行了文献综述，发现另有12例报告病例。总结了人口统计学、临床表现、预后因素、治疗及结果。尽管有个别病例报告，但（）性心内膜炎是可能发生的，应使用准确的诊断方法及时、正确地识别。对其流行病学、发病机制、抗菌药物耐药性及宿主相互作用持续开展研究，对于增进我们的认识及改进临床管理策略至关重要。
