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骨科中的纳米结构:推进诊断、靶向治疗和组织再生

Nanostructures in Orthopedics: Advancing Diagnostics, Targeted Therapies, and Tissue Regeneration.

作者信息

Frączek Wiktoria, Kotela Andrzej, Kotela Ireneusz, Grodzik Marta

机构信息

Department of Nanobiotechnology, Institute of Biology, Warsaw University of Life Sciences (WULS-SGGW), 02-787 Warsaw, Poland.

Faculty of Medicine, Collegium Medicum, Cardinal Stefan Wyszyński University, 01-938 Warsaw, Poland.

出版信息

Materials (Basel). 2024 Dec 17;17(24):6162. doi: 10.3390/ma17246162.

Abstract

Nanotechnology, delving into the realm of nanometric structures, stands as a transformative force in orthopedics, reshaping diagnostics, and numerous regenerative interventions. Commencing with diagnostics, this scientific discipline empowers accurate analyses of various diseases and implant stability, heralding an era of unparalleled precision. Acting as carriers for medications, nanomaterials introduce novel therapeutic possibilities, propelling the field towards more targeted and effective treatments. In arthroplasty, nanostructural modifications to implant surfaces not only enhance mechanical properties but also promote superior osteointegration and durability. Simultaneously, nanotechnology propels tissue regeneration, with nanostructured dressings emerging as pivotal elements in accelerating wound healing. As we navigate the frontiers of nanotechnology, ongoing research illuminates promising avenues for further advancements, assuring a future where orthopedic practices are not only personalized but also highly efficient, promising a captivating journey through groundbreaking innovations and tailored patient care.

摘要

纳米技术深入到纳米结构领域,在骨科领域堪称一股变革力量,重塑着诊断方式以及众多再生干预手段。从诊断方面说起,这一科学学科使对各种疾病和植入物稳定性的精确分析成为可能,开创了一个精度无与伦比的时代。纳米材料作为药物载体,带来了新的治疗可能性,推动该领域朝着更具针对性和有效性的治疗方向发展。在关节成形术中,对植入物表面进行纳米结构修饰不仅能增强机械性能,还能促进更好的骨整合和耐久性。同时,纳米技术推动组织再生,纳米结构敷料成为加速伤口愈合的关键要素。在我们探索纳米技术前沿的过程中,正在进行的研究为进一步发展照亮了充满希望的道路,确保了骨科医疗实践不仅能够个性化,而且高效的未来,预示着将通过突破性创新和量身定制的患者护理开启一段引人入胜的旅程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/11677186/22c892ea3202/materials-17-06162-g001.jpg

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