Shanks C A, Wade L D, Meyer R, Wilkinson C J
Anaesth Intensive Care. 1985 Feb;13(1):12-7. doi: 10.1177/0310057X8501300102.
Changes in body temperature were assessed in ten adult patients undergoing surgery involving cardiopulmonary bypass (CPB) and induced hypothermia. Intraoperatively, in comparable time intervals before CPB and after rewarming, the patients lost body heat. Between the time of induction of anaesthesia and CPB, the temperature of blood in the pulmonary artery fell 1.46 (SD 0.28 degrees C); between CPB and the end of surgery the fall was 1.55 (SD 0.86 degrees C). The extent of spontaneous hypothermia did not correlate with the amount of subcutaneous fat. Hypothermia was induced to obtain a stable deep body temperature of 27.2 (SD 1.3) degrees C, when mean skin temperature averaged 2 degrees C higher. The CPB machine returned approximately 2000 kJ of heat in the rewarming period, to produce pulmonary artery and mean skin temperatures of 37.1 (SD 0.7) degrees C and 31.4 (SD 2.1) degrees C respectively. Intraoperative deep body temperatures demonstrated the expected exponential relationship with metabolic rate. Postoperatively, increase in metabolic rate was associated with rising deep body and skin temperatures. Low resistance to the flow of heat toward the skin surface was demonstrated by low postoperative values for thermal insulation, which may indicate good peripheral perfusion seen during continuing vasodilator therapy.
对10名接受涉及体外循环(CPB)和诱导性低温的手术的成年患者的体温变化进行了评估。术中,在CPB前和复温后的可比时间间隔内,患者体温下降。在麻醉诱导至CPB期间,肺动脉血温下降1.46(标准差0.28摄氏度);在CPB至手术结束期间,下降幅度为1.55(标准差0.86摄氏度)。自发性低温的程度与皮下脂肪量无关。诱导低温以获得稳定的深部体温27.2(标准差1.3)摄氏度,此时平均皮肤温度平均高2摄氏度。CPB机在复温期返回约2000千焦的热量,使肺动脉和平均皮肤温度分别达到37.1(标准差0.7)摄氏度和31.4(标准差2.1)摄氏度。术中深部体温与代谢率呈现预期的指数关系。术后,代谢率增加与深部体温和皮肤温度升高相关。术后热绝缘值较低表明对流向皮肤表面的热流阻力较低,这可能表明在持续血管扩张剂治疗期间外周灌注良好。