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汽车使用者因吸入挥发性有机化合物和羰基化合物而面临的急性和慢性健康风险评估

Acute and Chronic Health Risk Assessment for Automobile Users Due to Inhalation Exposure to Volatile Organic Compounds and Carbonyl Compounds.

作者信息

Jeon Jeong-In, Lim Eun-Ju, Byun Young-Jun, Kim Min-Kwang, Lee Hyun-Woo, Kim Cha-Ryung, Park In-Ji, Kim Ho-Hyun, Lee Cheol-Min

机构信息

Department of Chemical and Environmental Engineering, Seokyeong University, Seoul 02713, Republic of Korea.

Korea Testing Laboratory, Seoul 08389, Republic of Korea.

出版信息

Toxics. 2024 Nov 24;12(12):843. doi: 10.3390/toxics12120843.

DOI:10.3390/toxics12120843
PMID:39771058
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11679100/
Abstract

Since automobiles are the primary means of transportation in modern society, the assessment of health effects from acute and chronic exposure to pollutants in automobiles is crucial. In this study, the concentration of volatile organic compounds (VOCs), carbonyl compounds, and odor-including substances in newly manufactured automobiles were analyzed, and exposure factors reflecting automobile user characteristics were selected for health risk assessment. Toluene exhibited the highest concentration (203.5 ± 379.3 μg/m) among all measured pollutants. The acute and chronic non-carcinogenic health risk assessments indicated that the pollutants did not exceed their standards in any of the automobiles, suggesting no immediate health risks. However, in the chronic carcinogenic health risk assessment, acrylonitrile exceeded its standard value in all automobiles, indicating potential carcinogenic effects from long-term exposure. The findings suggest that careful estimation of lifetime exposure effects to pollutants inside new automobiles is required. Future studies should investigate specific pollutants generated by automotive materials and manufacturing processes to identify pollutant sources and reduce health risks to automobile users.

摘要

由于汽车是现代社会的主要交通工具,评估急性和慢性暴露于汽车污染物对健康的影响至关重要。在本研究中,分析了新生产汽车中挥发性有机化合物(VOCs)、羰基化合物和含气味物质的浓度,并选择反映汽车使用者特征的暴露因素进行健康风险评估。在所有测量的污染物中,甲苯的浓度最高(203.5±379.3μg/m)。急性和慢性非致癌健康风险评估表明,所有汽车中的污染物均未超过标准,这表明不存在直接健康风险。然而,在慢性致癌健康风险评估中,丙烯腈在所有汽车中均超过其标准值,这表明长期接触可能具有致癌作用。研究结果表明,需要仔细估计新汽车内污染物的终生暴露影响。未来的研究应调查汽车材料和制造过程产生的特定污染物,以确定污染源并降低对汽车使用者的健康风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb48/11679100/2198c89c1add/toxics-12-00843-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb48/11679100/1d6f3672ef09/toxics-12-00843-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb48/11679100/7dcac17ce1da/toxics-12-00843-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb48/11679100/29035d80a27e/toxics-12-00843-g003a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb48/11679100/2198c89c1add/toxics-12-00843-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb48/11679100/1d6f3672ef09/toxics-12-00843-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb48/11679100/7dcac17ce1da/toxics-12-00843-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb48/11679100/29035d80a27e/toxics-12-00843-g003a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb48/11679100/2198c89c1add/toxics-12-00843-g004a.jpg

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Personal and community-level exposure to air pollution and daily changes in respiratory symptoms and oxygen saturation among adults with COPD.慢性阻塞性肺疾病(COPD)成人患者个人及社区层面的空气污染暴露与呼吸道症状和血氧饱和度的每日变化
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