Owen H, Galloway D J, Mitchell K G
Ann R Coll Surg Engl. 1985 Mar;67(2):114-5.
Wound infiltration with bupivacaine provided complete postoperative pain relief in 14 of 19 women undergoing excision biopsy of a benign breast lump under general anaesthesia. Fifteen patients formed a control group in whom the wound was infiltrated with saline. They had inadequate relief of pain despite receiving significantly more opioid analgesia than the bupivacaine group in the postoperative period. The analgesia from bupivacaine usually outlasted the postoperative pain. No adverse reactions were apparent.
在全身麻醉下对19名接受良性乳腺肿块切除活检的女性进行伤口浸润布比卡因,其中14名女性术后疼痛完全缓解。15名患者组成对照组,其伤口用生理盐水浸润。尽管在术后期间接受的阿片类镇痛药比布比卡因组多得多,但他们的疼痛缓解不充分。布比卡因产生的镇痛作用通常比术后疼痛持续时间更长。未观察到明显的不良反应。