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磁共振成像在评估早期子宫内膜癌和宫颈癌保留生育功能治疗可行性中的作用

Role of MRI in Assessing the Feasibility of Fertility-Sparing Treatments for Early-Stage Endometrial and Cervical Cancers.

作者信息

Lee Mihan, Andrieu Pamela I Causa, Nougaret Stephanie, Russo Luca, Moufarrij Sara, Mueller Jennifer J, Abu-Rustum Nadeem R, Menias Christine O, Lakhman Yulia

机构信息

Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065.

Department of Radiology, Weill Cornell Medical College, New York, NY.

出版信息

AJR Am J Roentgenol. 2025 Mar;224(3):e2432157. doi: 10.2214/AJR.24.32157. Epub 2025 Jan 8.

Abstract

Fertility-sparing treatment (FST) has become a key aspect of managing gynecologic cancers in reproductive-age patients who wish to preserve fertility. Several leading clinical societies, including the European Society of Gynecological Oncology, the European Society for Radiotherapy and Oncology, the European Society of Pathology, and the European Society of Human Reproduction and Embryology, have published evidence-based guidelines on fertility-sparing strategies and post-treatment surveillance of patients with early-stage gynecologic cancers, in particular endometrial and cervical cancers. These guidelines highlight MRI as essential to initial patient selection and follow-up. Properly tailored pelvic MRI protocols and clear MRI reports are key to performing accurate staging, assessing eligibility, and confirming the initial and ongoing feasibility of FST. Accordingly, radiologists, particularly those specializing in gynecologic imaging, play a critical role in the multidisciplinary approach to FST. They should be well-versed in FST eligibility criteria and key MRI findings before and after FST, ensuring these details are comprehensively communicated in structured MRI reports.

摘要

保留生育功能治疗(FST)已成为管理希望保留生育能力的育龄期妇科癌症患者的关键环节。包括欧洲妇科肿瘤学会、欧洲放射治疗与肿瘤学会、欧洲病理学会以及欧洲人类生殖与胚胎学会在内的多个主要临床学会,已发布了关于早期妇科癌症(尤其是子宫内膜癌和宫颈癌)患者保留生育功能策略及治疗后监测的循证指南。这些指南强调MRI对于初始患者选择和随访至关重要。恰当定制的盆腔MRI检查方案及清晰的MRI报告是进行准确分期、评估适用性以及确认FST初始及持续可行性的关键。因此,放射科医生,尤其是那些专门从事妇科影像诊断的医生,在FST的多学科治疗方法中发挥着关键作用。他们应精通FST的适用标准以及FST前后的关键MRI表现,确保在结构化MRI报告中全面传达这些细节。

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