Balus L, Bassetti F, Gentili G
Arch Dermatol. 1985 Feb;121(2):250-2.
A 39-year-old man had a two-year history of three indurated plaques that progressively underwent a cutis laxa-like transformation. Histopathologically a granulomatous, deep, dermal infiltrate was observed. It was composed mainly of numerous histiocytes and many multinucleate cells and foam cells. The case has the clinical and microscopic features of granulomatous slack skin (GSS), which may be considered to be a peculiar form of localized elastolysis. To date, there is no effective therapy for GSS.
一名39岁男性有3个硬结性斑块,病程两年,逐渐出现皮肤松弛样改变。组织病理学检查可见肉芽肿性、深部真皮浸润。主要由大量组织细胞、许多多核细胞和泡沫细胞组成。该病例具有肉芽肿性皮肤松弛症(GSS)的临床和显微镜特征,GSS可被认为是一种特殊形式的局限性弹性组织溶解症。迄今为止,尚无治疗GSS的有效方法。