Arosish D
Department of General Surgery, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Thandalam, Chennai, Tamil Nadu, India.
Med J Malaysia. 2025 Jan;80(Suppl 1):80-83.
Seborrheic keratosis (SK) is a prevalent hyperkeratotic dermatological condition characterized by benign proliferation of epidermal keratinocytes, typically occurring in the middle to advanced stages of life. While the trunk is the primary site for lesions, they can also manifest on the extremities, face, and scalp. Although SK is typically benign, there can be morphological overlap with malignant skin lesions, necessitating meticulous differentiation for an accurate diagnosis. This case report describes a 63-year-old male presenting with scalp swelling that was, initially suspected to be malignant. However, histopathological examination revealed pigmented seborrheic keratosis, prompting the need for a comprehensive management approach. Surgical excision with a rotational flap cover was performed successfully, highlighting the importance of precise diagnosis and management in addressing cutaneous lesions. The exact etiology of SK remains elusive, with potential genetic associations implicated in its pathogenesis. Although treatment may not always be necessary, various modalities are available for lesion removal or symptom management, with surgical intervention reserved for cases exhibiting signs of malignancy. Clinicians should be aware of the atypical presentations of SK and, emphasize the need for a multidisciplinary approach involving dermatologists, pathologists, and surgeons for optimal outcomes.
脂溢性角化病（SK）是一种常见的角化过度性皮肤病，其特征为表皮角质形成细胞的良性增殖，通常发生在中年至老年阶段。虽然躯干是病变的主要部位，但也可出现在四肢、面部和头皮上。尽管SK通常为良性，但在形态上可能与恶性皮肤病变重叠，因此需要进行细致的鉴别以做出准确诊断。本病例报告描述了一名63岁男性，其头皮肿胀最初被怀疑为恶性。然而，组织病理学检查显示为色素性脂溢性角化病，这提示需要采取综合管理方法。成功实施了带旋转皮瓣覆盖的手术切除，突出了精确诊断和管理在处理皮肤病变中的重要性。SK的确切病因仍不明确，其发病机制可能与潜在的基因关联有关。虽然并非总是需要治疗，但有多种方法可用于去除病变或管理症状，手术干预仅适用于表现出恶性迹象的病例。临床医生应了解SK的非典型表现，并强调需要皮肤科医生、病理科医生和外科医生参与的多学科方法以获得最佳结果。
