Gopal Purva, Hu Xiaobang, Robert Marie E, Zhang Xuchen
Deparment of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Department of Pathology and Laboratory Medicine, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Hepatol Commun. 2025 Jan 7;9(1). doi: 10.1097/HC9.0000000000000628. eCollection 2025 Jan 1.
Histopathologic evaluation of liver biopsy has played a longstanding role in the diagnosis and management of liver disease. However, the utility of liver biopsy has been questioned by some, given the improved imaging modalities, increased availability of noninvasive serologic tests, and development of artificial intelligence over the past several years. In this review, we discuss the current and future role of liver biopsy in both non-neoplastic and neoplastic liver diseases in the era of improved noninvasive laboratory, radiologic, and digital technologies.
肝活检的组织病理学评估在肝病的诊断和管理中一直发挥着重要作用。然而，鉴于过去几年成像方式的改进、非侵入性血清学检测的可用性增加以及人工智能的发展，一些人对肝活检的实用性提出了质疑。在这篇综述中，我们讨论了在非侵入性实验室、放射学和数字技术不断改进的时代，肝活检在非肿瘤性和肿瘤性肝病中的当前及未来作用。
