Li Yuyang, Hou Lili, Gan Xing, Yang Xi
School of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Nursing Department, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Sci Rep. 2025 Jan 7;15(1):1094. doi: 10.1038/s41598-024-83081-4.
This study was conducted by searching electronic databases from January 1, 2000 to August 8, 2023: Web of Science, PubMed, Cochrane Library, Embase, Scopus, Google Scholar, China Biomedical Literature Database (CBM), China National Knowledge Network (CNKI), China Science and Technology Journal Database (VIP) and Wan-fang Database were included in 14 studies with a total sample size of 1630 cases. This study conducted a meta-analysis of the literature published in recent years on the occurrence of dysgeusia in Head and neck squamous cell carcinoma (HNSCC) patients with non-pharmacological treatment, in order to provide the latest evidence-based evidence for medical staff and provide a basis for further intervention of dysgeusia in HNSCC patients. Compared with conventional care in the control group, In the experimental group, the non-pharmacological intervention reduced the score of dysgeusia [MD = - 0.76, 95% CI (- 1.04, - 0.48), P < 0.00001] and the incidence of dysgeusia [MD = 0.17, 95% CI (0.09, 0.31), P < 0.00001].
本研究通过检索2000年1月1日至2023年8月8日的电子数据库进行：纳入了Web of Science、PubMed、Cochrane图书馆、Embase、Scopus、谷歌学术、中国生物医学文献数据库（CBM）、中国知网（CNKI）、中国科技期刊数据库（VIP）和万方数据库，14项研究的总样本量为1630例。本研究对近年来发表的关于头颈部鳞状细胞癌（HNSCC）患者非药物治疗中味觉障碍发生情况的文献进行了荟萃分析，以便为医务人员提供最新的循证依据，并为进一步干预HNSCC患者的味觉障碍提供依据。与对照组的常规护理相比，在实验组中，非药物干预降低了味觉障碍评分[MD = - 0.76，95% CI（- 1.04，- 0.48），P < 0.00001]和味觉障碍发生率[MD = 0.17，95% CI（0.09，0.31），P < 0.00001]。
