Ben-Eli Hadas, Cnaany Yaacov, Halpert Michael, Chowers Itay, Goldstein Ayelet
Department of Ophthalmology, Hadassah-Hebrew University Medical Center, POB 12000, 91120, Jerusalem, Israel.
Department of Optometry and Vision Science, Hadassah Academic College, Jerusalem, Israel.
Sci Rep. 2025 Jan 7;15(1):1242. doi: 10.1038/s41598-024-84382-4.
Cataract surgery, a common procedure for vision restoration, exhibits variable outcomes based on patient demographics. This study aimed to elucidate the effects of age and sex on risk factors, intraoperative complications, and postoperative outcomes of cataract surgery. A single-center retrospective cohort study analyzed 691 eyes from 589 individuals who underwent surgery at a tertiary referral center, using electronic medical records to assess preoperative risk factors, intraoperative complications, and best corrected visual acuity (BCVA) pre- and post-operatively, alongside demographic data. The study found that males aged 65-75 years had significantly higher rates of functional postoperative BCVA (91% for males vs. 79% for females, p = 0.007), a disparity not attributable to differences in surgical complications or risk factor prevalence. Age-specific thresholds were identified where BCVA improvements significantly declined beyond 65 years for females and 75 years for males. The likelihood of worsened BCVA post-surgery increased with age for both sexes, with a notable decline in BCVA improvement between the 55-65 years and 65-75 years age groups. These findings underscore the critical influence of sex and age on cataract surgery outcomes, advocating for the integration of these factors into preoperative evaluations to better tailor the timing and planning of cataract surgery and optimize clinical outcomes.
白内障手术是一种常见的视力恢复手术，其结果因患者人口统计学特征而异。本研究旨在阐明年龄和性别对白内障手术的危险因素、术中并发症及术后结果的影响。一项单中心回顾性队列研究分析了来自一家三级转诊中心的589名患者的691只眼睛，利用电子病历评估术前危险因素、术中并发症以及术前和术后的最佳矫正视力（BCVA），同时收集人口统计学数据。研究发现，65至75岁的男性术后功能性BCVA显著更高（男性为91%，女性为79%，p = 0.007），这种差异并非由手术并发症或危险因素患病率的差异所致。确定了特定年龄阈值，即女性超过65岁、男性超过75岁后，BCVA改善显著下降。两性术后BCVA恶化的可能性均随年龄增加，在55至65岁和65至75岁年龄组之间，BCVA改善显著下降。这些发现强调了性别和年龄对白内障手术结果的关键影响，主张将这些因素纳入术前评估，以更好地调整白内障手术的时机和规划，优化临床结果。
