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理解三重周期极小曲面骨支架的孔隙结构与性能之间的关系。

Understanding the relationship between pore structure and properties of triply periodic minimal surface bone scaffolds.

作者信息

Sun Yadi, Wang Yan, Dong Benchao, Yang Peichuan, Ji Chunhui, Li Yiyang, Ma Jianxiong, Ma Xinlong

机构信息

Tianjin Hospital Tianjin University, Tianjin, China.

Tianjin Orthopedic Institute, Tianjin, China.

出版信息

J Mater Sci Mater Med. 2025 Jan 7;36(1):6. doi: 10.1007/s10856-024-06856-1.

Abstract

The number of patients with bone defects caused by trauma and diseases has been increasing year by year. The treatment of bone defects remains a major challenge in clinical practice. Bone scaffolds are increasingly favored for repairing bones, with triply periodic minimal surface (TPMS) scaffolds emerging as a popular option due to their superior performance. The aim of this review is to highlight the crucial influence of pore structure on the properties of TPMS bone scaffolds, offering important insights for their innovation and production. It briefly examines various elements that influence the properties of TPMS bone scaffolds, such as pore shape, porosity, pore diameter, and curvature. By analyzing these elements, this review serves as a valuable reference for upcoming research and practical implementations in the field of bone tissue engineering.

摘要

因创伤和疾病导致骨缺损的患者数量逐年增加。骨缺损的治疗仍是临床实践中的一项重大挑战。骨支架在骨修复方面越来越受到青睐,其中三重周期极小曲面(TPMS)支架因其卓越性能成为热门选择。本综述的目的是强调孔隙结构对TPMS骨支架性能的关键影响,为其创新和生产提供重要见解。它简要考察了影响TPMS骨支架性能的各种因素,如孔隙形状、孔隙率、孔径和曲率。通过分析这些因素,本综述为骨组织工程领域未来的研究和实际应用提供了有价值的参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b4f/11706857/605ba64bf94d/10856_2024_6856_Fig1_HTML.jpg

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