Hellner Megan, Cai Kelly, Freestone Dave, Baker Jessica H, Menzel Jessie, Steinberg Dori M
Research, Equip Health Inc, Carlsbad, USA.
Int J Eat Disord. 2025 Apr;58(4):680-689. doi: 10.1002/eat.24355. Epub 2025 Jan 7.
Treatment outcomes research for avoidant/restrictive food intake disorder (ARFID) has been limited to small, mixed-age feasibility trials in face-to-face care settings. This study aims to examine clinical characteristics and treatment outcomes in a large sample of youth and adult patients receiving virtual multidisciplinary team treatment for ARFID.
The sample included N = 783 patients (532 youth and 251 adults) diagnosed with ARFID. Patients received cognitive behavioral therapy for ARFID (CBT-AR) or family-based treatment for ARFID (FBT-ARFID) enhanced by specialized support from a multidisciplinary team. Patients (or caregivers) completed a number of measures assessing ARFID and mood-related symptoms upon admission and throughout treatment.
Youth patients on weight restoration (56%) started treatment around 85% [84%, 86%] of their target weight, and increased to 94% [93%, 96%] by week 35. Adults on weight restoration (47%) started at 85% [84%, 87%] and reached 92% [90%, 94%]. Scores improved for both groups on all PARDI-AR-Q subscales: (sensory sensitivity: b = -0.25 [-0.33, -0.16]; lack of interest: b = -0.08 [-0.16, -0.00]; fear of aversive consequences: b = -0.12 [-0.19, -0.04]). Both youth and adults demonstrated reliable improvements in willingness to try new foods (b = -0.64 [-0.89, -0.37]), anxiety symptoms (b = -0.71 [-0.95, -0.48]), and depression symptoms (b = -0.86 [-1.07, -0.64]).
Youth and adult patients demonstrated reliable symptom improvements over the course of treatment across all measures, offering preliminary support for the effectiveness of FBT-ARFID and CBT-AR delivered virtually by a multidisciplinary care team.
回避/限制性食物摄入障碍(ARFID)的治疗效果研究仅限于在面对面护理环境中进行的小规模、不同年龄段的可行性试验。本研究旨在调查接受ARFID虚拟多学科团队治疗的大量青少年和成年患者的临床特征及治疗效果。
样本包括783例被诊断为ARFID的患者(532例青少年和251例成年人)。患者接受针对ARFID的认知行为疗法(CBT-AR)或在多学科团队的专门支持下加强的针对ARFID的家庭治疗(FBT-ARFID)。患者(或照顾者)在入院时及整个治疗过程中完成了多项评估ARFID和情绪相关症状的测量。
体重恢复中的青少年患者(56%)开始治疗时体重约为目标体重的85%[84%,86%],到第35周时增至94%[93%,96%]。体重恢复中的成年患者(47%)开始时体重为85%[84%,87%],达到92%[90%,94%]。两组在所有PARDI-AR-Q子量表上的得分均有所改善:(感官敏感性:b=-0.25[-0.33,-0.16];缺乏兴趣:b=-0.08[-0.16,-0.00];对厌恶后果的恐惧:b=-0.12[-0.19,-0.04])。青少年和成年人在尝试新食物的意愿(b=-0.64[-0.89,-0.37])、焦虑症状(b=-0.71[-0.95,-0.48])和抑郁症状(b=-0.86[-1.07,-0.64])方面均表现出可靠的改善。
青少年和成年患者在整个治疗过程中的所有测量指标上均表现出可靠的症状改善,为多学科护理团队以虚拟方式提供的FBT-ARFID和CBT-AR的有效性提供了初步支持。