Feng Nenggui, Zhao Wei, Xiao Yunxin, Lin Jiajian, Ao Zhixian, Zhang Chengjie, Chen Guangyao
Department of Urology, People's Hospital of Yangjiang (Affiliated Hospital of Guangdong Medical University, Yangjiang), Yangjiang, 529500, China.
Department of Urology, Anqing 116 Hospital, Anqing, 246003, China.
Int Urol Nephrol. 2025 Jun;57(6):1763-1770. doi: 10.1007/s11255-024-04359-0. Epub 2025 Jan 7.
To evaluate and compare the efficacy of a newly designed in-house assistive internal fluid circulatory device in ureteroscopic lithotripsy for ureteral stones.
In this study, 97 patients were assigned to the trial group and underwent ureteroscopic lithotripsy with an in-house newly designed assistive internal fluid circulatory device; 96 patients were assigned to the control group and underwent traditional ureteroscopic lithotripsy without the assistive device. The primary outcome was the final stone-free rate (SFR) at 1-month post-surgery. Secondary observations included the quality of the surgical field, difficulty experienced during insertion of the ureteroscope, stone migration rate, operative time, change in serum creatinine, changes in the urinary leukocyte count, and perioperative complications.
No significant differences were detected between the two groups in terms of gender, age, body mass index, location, or stone burden (P > 0.05). At the 1-month follow-up, the SFR was significantly higher in the trial group than the control group (P < 0.05). Furthermore, the operative time was significantly shorter in the trial group (P < 0.05) with easier ureteroscope insertion relative to the control group (P < 0.05). The incidence of stone migration in the trial group was significantly lower than that in the control group (P < 0.05) and the quality of the surgical field was significantly improved (P < 0.001). No significant differences were detected in terms of serum creatinine levels, urinary leukocyte counts, or perioperative complications (P > 0.05).
The application of an assistive internal fluid circulatory device represents an effective and safe method for ureteroscopic lithotripsy.
评估并比较一种新设计的内部辅助液体循环装置在输尿管镜碎石术治疗输尿管结石中的疗效。
本研究中，97例患者被分配至试验组，采用新设计的内部辅助液体循环装置进行输尿管镜碎石术；96例患者被分配至对照组，接受无辅助装置的传统输尿管镜碎石术。主要结局指标为术后1个月时的最终无石率（SFR）。次要观察指标包括手术视野质量、输尿管镜插入难度、结石移位率、手术时间、血清肌酐变化、尿白细胞计数变化及围手术期并发症。
两组在性别、年龄、体重指数、结石位置或结石负荷方面均未检测到显著差异（P>0.05）。在1个月随访时，试验组的SFR显著高于对照组（P<0.05）。此外，试验组的手术时间显著缩短（P<0.05），且相对于对照组，输尿管镜插入更容易（P<0.05）。试验组的结石移位发生率显著低于对照组（P<0.05），手术视野质量显著改善（P<0.001）。在血清肌酐水平、尿白细胞计数或围手术期并发症方面未检测到显著差异（P>0.05）。
应用内部辅助液体循环装置是输尿管镜碎石术的一种有效且安全的方法。
