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基于德国健康保险索赔数据的输尿管镜检查、体外冲击波碎石术和经皮肾镜取石术后尿石症再干预的结果和成本的长期评估。

Long-term evaluation of outcomes and costs of urolithiasis re-interventions after ureteroscopy, extracorporeal shockwave lithotripsy and percutaneous nephrolithotomy based on German health insurance claims data.

机构信息

Department of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.

Department of Urology, Asklepios Hospital Barmbek, Hamburg, Germany.

出版信息

World J Urol. 2022 Dec;40(12):3021-3027. doi: 10.1007/s00345-022-04180-3. Epub 2022 Oct 14.

Abstract

PURPOSE

Comparisons of ureteroscopy (URS), extracorporeal shockwave lithotripsy (SWL) and percutaneous nephrolithotomy (PCNL) for urolithiasis considering long-term follow-up are rare. We aimed to analyze re-intervention rates, costs and sick leave days of URS, SWL and PCNL patients within 7 years.

METHODS

This retrospective cohort study was based on German health insurance claims data. We included 54,609 urolithiasis patients incidentally treated in 2008-2010. We investigated time to re-intervention, number of sick leave days and healthcare costs. We applied negative binomial, extended Cox regression and gamma models.

RESULTS

54% were incidentally treated with URS, 40% with SWL and 6% with PCNL. 15% of URS, 26% of SWL and 23% of PCNL patients were re-treated within 7 years. Time to re-intervention was significantly lower for PCNL (955 days) and SWL (937 days) than URS (1078 days) patients. Costs for incident treatment were significantly higher for PCNL (2760€) and lower for SWL (1342€) than URS (1334€) patients. Yet, total costs including re-interventions were significantly higher for PCNL (5783€) and SWL (3240€) than URS (2979€) patients. Total number of sick leave days was increased for PCNL (13.0 days) and SWL (10.1 days) compared to URS (6.8 days) patients.

CONCLUSION

This study describes outcomes after use of different intervention options for urolithiasis. URS patients showed longest time free of re-interventions and lowest number of sick leave days. Although SWL patients initially had lower costs, URS patients had lower costs in the long run. PCNL patients showed high costs and sick leave days.

摘要

目的

比较输尿管镜检查术(URS)、体外冲击波碎石术(SWL)和经皮肾镜取石术(PCNL)治疗尿路结石的长期随访结果,此类研究较为罕见。本研究旨在分析 URS、SWL 和 PCNL 患者在 7 年内的再干预率、成本和病假天数。

方法

这是一项基于德国健康保险索赔数据的回顾性队列研究。我们纳入了 2008 年至 2010 年期间偶然接受治疗的 54609 例尿路结石患者。我们调查了再干预时间、病假天数和医疗保健成本。我们应用了负二项式、扩展 Cox 回归和伽马模型。

结果

54%的患者偶然接受了 URS 治疗,40%的患者接受了 SWL 治疗,6%的患者接受了 PCNL 治疗。15%的 URS、26%的 SWL 和 23%的 PCNL 患者在 7 年内需要再次治疗。PCNL(955 天)和 SWL(937 天)患者的再干预时间明显短于 URS(1078 天)患者。PCNL(2760 欧元)和 SWL(1342 欧元)的初始治疗费用明显高于 URS(1334 欧元)患者,而包括再干预在内的总费用则明显高于 URS(2979 欧元)患者。PCNL(13.0 天)和 SWL(10.1 天)患者的总病假天数均高于 URS(6.8 天)患者。

结论

本研究描述了不同尿路结石干预措施的结果。URS 患者无再干预的时间最长,病假天数最少。虽然 SWL 患者的初始费用较低,但 URS 患者的长期费用较低。PCNL 患者的费用和病假天数较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb0c/9712271/5697e8bc3f22/345_2022_4180_Fig1_HTML.jpg

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