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前列腺激光汽化术:保留射精功能与不保留射精功能技术的比较研究

"Laser vaporization of the prostate: A comparative study between ejaculatory preserving and non-ejaculatory preserving technique".

作者信息

Emam Ahmed, Nabil Habib Kirolos, Teama Khaled, Samir Younan, Sadeq Mohammed Metwally, Gamal Mohamed A

机构信息

Faculty of Medicine, Urology Department, Ain Shams University, Cairo, Egypt.

出版信息

Arab J Urol. 2024 Jul 4;23(1):8-15. doi: 10.1080/20905998.2024.2375677. eCollection 2025.

Abstract

INTRODUCTION AND OBJECTIVES

Laser vaporization techniques have emerged as a prominent alternative to transurethral prostate resection in managing benign prostatic obstruction (BPO). This study focuses on assessing the effectiveness of the ejaculatory preserving laser vaporization of the prostate technique compared to the conventional non-ejaculatory approach in managing BPO.

PATIENTS AND METHODS

Our study was performed between August 2022 and September 2023. The study included 120 patients with bladder outlet obstruction, due to benign prostatic hyperplasia (BPH). Patients were randomly assigned to two groups: the first underwent conventional non-ejaculatory preserving laser vaporization of the prostate ( = 80), while the second group underwent the innovative ejaculatory preserving laser vaporization technique using diode laser ( = 40). We assessed baseline International Prostate Symptom Score (IPSS), maximal flow rate (Qmax), post voiding residual urine volume (PVRU), semen volume (semen analysis). Parameters were re-evaluated 3 months post-surgery and the change in sexual satisfaction was evaluated using a scale from 1 (much less satisfied) to 5 (much more satisfied) in response to a question.

RESULTS

The mean age (±SD) of participants was 59.6 (±7.9) and 57.6 (±7.8) for the non-ejaculatory preserving and ejaculatory preserving groups, respectively, with no statistical difference between groups. Both groups showed significant reduction in IPSS ( < 0.001), improvement in Qmax ( < 0.001), and decline in PVRU ( < 0.001), postoperatively. However, the ejaculatory preserving technique led to a significant improvement in antegrade ejaculation, postoperative semen volume and sexual satisfaction compared to the non-ejaculatory preserving technique ( < 0.001).

CONCLUSIONS

The ejaculatory preserving technique effectively preserved antegrade ejaculation, semen volume and sexual satisfaction compared to the non-ejaculatory preserving technique. However, the later yielded better outcomes in terms of IPSS and urine flow. Both techniques demonstrated significant improvements across all parameters compared to baseline. Further research with extended follow-up periods is needed to fully understand the long-term postoperative effects with this technique.

摘要

引言与目的

在治疗良性前列腺梗阻(BPO)方面,激光汽化技术已成为经尿道前列腺切除术的一种重要替代方法。本研究旨在评估保留射精功能的前列腺激光汽化技术与传统不保留射精功能的方法相比,在治疗BPO中的有效性。

患者与方法

我们的研究于2022年8月至2023年9月进行。该研究纳入了120例因良性前列腺增生(BPH)导致膀胱出口梗阻的患者。患者被随机分为两组:第一组接受传统的不保留射精功能的前列腺激光汽化术(n = 80),而第二组接受使用二极管激光的创新性保留射精功能的激光汽化技术(n = 40)。我们评估了基线国际前列腺症状评分(IPSS)、最大尿流率(Qmax)、排尿后残余尿量(PVRU)、精液量(精液分析)。术后3个月重新评估各项参数,并通过一个问题,使用从1(非常不满意)到5(非常满意)的量表来评估性满意度的变化。

结果

不保留射精功能组和保留射精功能组参与者的平均年龄(±标准差)分别为59.6(±7.9)岁和57.6(±7.8)岁,两组之间无统计学差异。两组术后IPSS均显著降低(P < 0.001),Qmax均有所改善(P < 0.001),PVRU均下降(P < 0.001)。然而,与不保留射精功能的技术相比,保留射精功能的技术在顺行射精、术后精液量和性满意度方面有显著改善(P < 0.001)。

结论

与不保留射精功能的技术相比,保留射精功能的技术有效地保留了顺行射精、精液量和性满意度。然而,在IPSS和尿流方面,后者的效果更好。与基线相比,两种技术在所有参数上均表现出显著改善。需要进行更长随访期的进一步研究,以充分了解该技术的长期术后效果。

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