Lammers H A, Teunissen T A M, Bor H, Smid I S, Lagro-Janssen A L M
Radboudumc, Department of Primary and Community Care/Gender & Women's Health, Nijmegen, the Netherlands.
Res Rep Urol. 2020 May 5;12:167-174. doi: 10.2147/RRU.S241961. eCollection 2020.
Lower urinary tract symptom (LUTS) is a common condition in older men. In accordance with the Dutch College of General Practitioners Guideline "Micturition symptoms in men", the diagnosis can be made based on a patient's medical history and a physical examination. GPs lack additional tools in primary care to assess the residual urine volume. A residual volume usually requires a referral to a urologist. We hypothesized that the IPSS screening questionnaire score (measuring the severity of symptoms) might be related to patients' residual urine volume. The research objective was to examine the relation between the IPSS score and the residual urine volume.
In a cross-sectional study, we analysed patients' IPSS and residual urine volume. Men aged over 50 with LUTS who consulted Dutch primary-care physicians were included. The interventions comprised an IPSS screening and a bladder scan. Data regarding the patients' residual volume, total IPSS score, single IPSS score, IPSS storage score, and IPSS voiding score were recorded and analysed. We used odds ratios to describe the relation between the IPSS categories associated with the presence of a normal or abnormal (above 100 cc and above 200 cc) residual urine volume.
A total of 126 patients were included in this study. Patients with higher scores on the overall IPSS, separate IPSS, IPSS storage and IPSS voiding showed no higher odds ratios of having an abnormal residual volume, neither above 100 mL or 200 mL.
We did not find a relation between the IPSS core to an abnormal residual urine volume in men aged over 50 with LUTS consulting primary-care physicians.
This study has been approved by the Central Committee on Research Involving Human Subjects for the Arnhem-Nijmegen Region and is registered with ToetsingOnline under ID number 29822.091.10.
下尿路症状（LUTS）在老年男性中较为常见。根据荷兰全科医生学院“男性排尿症状”指南，可依据患者病史和体格检查做出诊断。全科医生在初级保健中缺乏评估残余尿量的额外工具。通常需要将患者转诊给泌尿科医生以测量残余尿量。我们推测国际前列腺症状评分（IPSS）筛查问卷分数（衡量症状严重程度）可能与患者的残余尿量有关。研究目的是探讨IPSS评分与残余尿量之间的关系。
在一项横断面研究中，我们分析了患者的IPSS和残余尿量。纳入了年龄超过50岁且有LUTS症状并咨询荷兰初级保健医生的男性。干预措施包括IPSS筛查和膀胱扫描。记录并分析了有关患者残余尿量、IPSS总分、单项IPSS评分、IPSS储尿期评分和IPSS排尿期评分的数据。我们使用优势比来描述与正常或异常（超过100毫升和超过200毫升）残余尿量相关的IPSS类别之间的关系。
本研究共纳入126例患者。总体IPSS、单项IPSS、IPSS储尿期和IPSS排尿期得分较高的患者，其残余尿量异常（超过100毫升或200毫升）的优势比并未升高。
对于咨询初级保健医生的年龄超过50岁且有LUTS症状的男性，我们未发现IPSS评分与异常残余尿量之间存在关联。
本研究已获得阿纳姆 - 奈梅亨地区人类受试者研究中央委员会的批准，并在ToetsingOnline上注册，注册号为29822.091.10。
