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体外受精后发生子宫颈和子宫的异位妊娠。经羊膜腔内注射杀胎药终止宫颈妊娠后成功分娩。

Post IVF heterotopic pregnancy with one in cervix and one in uterus. Successful delivery after termination of the cervical pregnancy with intraamniotic feticide.

作者信息

Michos G, Najdecki R, Valasoulis G, Daponte A, Mamopoulos A, Papanikolaou E G

机构信息

Third Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece.

Assisting Nature, Centre of Reproduction and Genetics, Thessaloniki, Greece.

出版信息

Int J Surg Case Rep. 2025 Feb;127:110832. doi: 10.1016/j.ijscr.2025.110832. Epub 2025 Jan 4.

Abstract

INTRODUCTION

Cervical pregnancy is a rare kind of ectopic pregnancy. Heterotopic pregnancy is a condition, where we have one sac in the uterus and one in another location, usually because of IVF treatment. This scenario can become a life-threatening condition, if remain untreated.

PRESENTATION OF CASE

A 44-year-old woman underwent IVF (egg donation) with double embryotransfer and resulted in twin pregnancy, however heterotopic. One in cervix and one intrauterine. Until 8 weeks both pregnancies evoluting equally and then a decision made to terminate the cervical one. Her physician chose a transabdominal approach (amniocentesis wise); however, this attempt failed. Then, intracervical puncture by a reproductive specialist was attempted with potassium chloride injection and aspiration of the amniotic fluid. The pregnancy was terminated successfully, and no complications presented afterwards. The intrauterine pregnancy evoluted normally and a livebirth was achieved at 39 weeks.

DISCUSSION

The current case represents an interesting way of terminating a cervical pregnancy even in the presence of a twin intrauterine sibling.

CONCLUSION

Patients with heterotopic pregnancies, should be encouraged not to terminate both pregnancies and to be referred in specialized reproductive and fetal maternity centers.

摘要

引言

宫颈妊娠是一种罕见的异位妊娠。异位妊娠是指子宫内有一个孕囊而另一个在其他部位的情况,通常是由于体外受精治疗所致。如果不进行治疗,这种情况可能会危及生命。

病例介绍

一名44岁女性接受了体外受精(卵子捐赠)并进行了双胚胎移植,结果怀了双胞胎,但属于异位妊娠。一个在宫颈,一个在子宫内。直到孕8周,两个妊娠进展均正常,之后决定终止宫颈内的妊娠。她的医生选择了经腹途径(类似羊膜穿刺术);然而,这次尝试失败了。随后,一名生殖专家尝试经宫颈穿刺并注射氯化钾及抽取羊水。妊娠成功终止,之后未出现并发症。子宫内的妊娠正常进展,孕39周时顺利分娩。

讨论

本病例展示了一种即使在子宫内怀有双胞胎的情况下终止宫颈妊娠的有趣方法。

结论

对于异位妊娠患者,应鼓励其不要终止两个妊娠,并转诊至专业的生殖和胎儿产科中心。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0151/11760322/5bf69167dc1e/gr1.jpg

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