Di Jeso B, Formisano S, Palumbo G
Biochem Biophys Res Commun. 1985 Feb 28;127(1):37-43. doi: 10.1016/s0006-291x(85)80122-4.
The present investigation demonstrates that the cross-linking agent, dimethylsuberimidate, is an usefull tool to study thyroglobulin structure. In fact, while reproducible and discrete polymerization products are obtained in strictly controlled conditions, valuable information on the native assemblage of thyroglobulin subunits and the effects of its major post-translational modification (iodination) on its structure, are reported.
本研究表明，交联剂辛二酸二甲酯亚胺是研究甲状腺球蛋白结构的有用工具。事实上，虽然在严格控制的条件下可获得可重复且离散的聚合产物，但有关甲状腺球蛋白亚基的天然组装及其主要翻译后修饰（碘化）对其结构的影响的有价值信息也已得到报道。
