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小儿(4.85Fr)与超微型(<15Fr)经皮肾镜取石术治疗学龄前儿童10-20mm肾结石的比较。

Comparison between Micro-(4.85Fr) and Ultramini-(<15Fr) percutaneous nephrolithotomy for the treatment of 10-20 mm kidney stones in preschool children.

作者信息

Li Chenglong, Zhao Youquan, Wang Wenying, Li Jun, Tian Ye, Ning Chen

机构信息

Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China; Institute of Urology, Beijing Municipal Health Commission, Beijing, 100050, China.

Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China; Institute of Urology, Beijing Municipal Health Commission, Beijing, 100050, China.

出版信息

J Pediatr Urol. 2025 Jun;21(3):584-590. doi: 10.1016/j.jpurol.2024.12.018. Epub 2024 Dec 28.

Abstract

INTRODUCTION

The incidence of kidney stones in children has steadily increased in recent years. Miniaturized percutaneous nephrolithotomy (PCNL) techniques, such as micro-PCNL(4.85Fr) and ultramini-PCNL(<15Fr), have become increasingly prevalent in pediatric kidney stone treatment due to their high stone clearance rate and low complication rate. This study aimed to compare the efficacy and safety of micro-PCNL and ultramini-PCNL in preschool children with 10-20 mm kidney stones.

PATIENTS AND METHODS

A retrospective analysis was performed on data from patients under 6 years who received micro-PCNL and ultramini-PCNL surgeries in our hospital between January 2020 and January 2024. The inclusion criteria consisted of pediatric patients (<6 years) with unilateral 10-20 mm kidney stones. Patients with urinary tract malformations or comorbidities were excluded from the study. Patient demographics, stone characteristics, and intra- and postoperative parameters were analyzed.

RESULTS

There were 33 patients in the micro-PCNL group and 31 patients in the ultramini-PCNL group, with a mean age of 3.1 ± 1.3 years and 3.6 ± 1.8 years (p = 0.208), respectively. The stone size was 15 ± 4 mm in the micro-PCNL group and 16 ± 4 mm in the ultramini-PCNL group (p = 0.326). Micro-PCNL and ultramini-PCNL groups showed comparable stone-free rates (84.8 % vs. 87.1 %, p = 0.796) and procedure times (49 ± 17 min vs. 54 ± 23 min, p = 0.218). However, a significantly shorter hospitalization period was observed in the micro-PCNL group compared with the ultramini-PCNL group (2.3 ± 1.3 days vs. 4.6 ± 2.2 days, p < 0.001). Complications were similar between groups, with 12.4 % in the micro-PCNL group and 16.1 % in the ultramini-PCNL group and no severe hematuria was observed.

CONCLUSIONS

In preschool children with 10-20 mm kidney stones, both micro-PCNL and ultramini-PCNL achieve similarly high stone-free rates with minimal complications, showing comparable outcomes in appropriately selected patients with experienced surgeons.

摘要

引言

近年来,儿童肾结石的发病率呈稳步上升趋势。小型化经皮肾镜取石术(PCNL)技术,如微通道PCNL(4.85Fr)和超微通道PCNL(<15Fr),因其高结石清除率和低并发症发生率,在儿童肾结石治疗中越来越普遍。本研究旨在比较微通道PCNL和超微通道PCNL治疗10 - 20mm肾结石学龄前儿童的疗效和安全性。

患者与方法

对2020年1月至2024年1月期间在我院接受微通道PCNL和超微通道PCNL手术的6岁以下患者的数据进行回顾性分析。纳入标准包括单侧10 - 20mm肾结石的儿科患者(<6岁)。排除有尿路畸形或合并症的患者。分析患者的人口统计学特征、结石特征以及术中和术后参数。

结果

微通道PCNL组有33例患者,超微通道PCNL组有31例患者,平均年龄分别为3.1±1.3岁和3.6±1.8岁(p = 0.208)。微通道PCNL组结石大小为15±4mm,超微通道PCNL组为16±4mm(p = 0.326)。微通道PCNL组和超微通道PCNL组的结石清除率相当(84.8%对87.1%,p = 0.796),手术时间也相当(49±17分钟对54±23分钟,p = 0.218)。然而,与超微通道PCNL组相比,微通道PCNL组的住院时间明显更短(2.3±1.3天对4.6±2.2天,p < 0.001)。两组并发症相似,微通道PCNL组为12.4%,超微通道PCNL组为16.1%,未观察到严重血尿。

结论

对于10 - 20mm肾结石的学龄前儿童,微通道PCNL和超微通道PCNL均能达到相似的高结石清除率,并发症极少,在经验丰富的外科医生选择合适的患者中显示出相当的疗效。

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