Souza Maria M C, Rocha Raquel G, Siqueira Gilvana P, Crapnell Robert D, Richter Eduardo M, Banks Craig E, Muñoz Rodrigo A A
Federal University of Uberlândia, Chemistry Institute, Uberlândia, MG, 38400-902, Brazil.
Faculty of Science and Engineering, Manchester Metropolitan University, Dalton Building, Chester Street, Manchester, Great Britain, M1 5GD, UK.
Mikrochim Acta. 2025 Jan 9;192(2):60. doi: 10.1007/s00604-024-06902-3.
The use of 3D-printed electrodes is reported fabricated from in-house conductive filament composed of a mixture of recycled poly (lactic acid) (rPLA), graphite (Gpt), and carbon black (CB) for fast detection of the abused drug ketamine. Firstly, the performance of these electrodes was evaluated in comparison to 3D-printed electrodes produced employing a commercially available conductive filament. After a simple pretreatment step (mechanical polishing), the new 3D-printed electrodes presented better performance than the electrodes produced from commercial filament in relation to peak-to-peak separation of the redox probe [Fe(CN)]/ (130 mV and 759 mV, respectively), charge transfer resistance (R = 1.04 ± 0.05 kΩ and 9.62 ± 0.03 kΩ, respectively), and heterogeneous rate constant (k = 7.16 ± 0.05 × 10 cm s and 3.57 ± 0.03 × 10 cm s, respectively). Excellent analytical characteristics for the detection of ketamine were achieved, including wide linear range (10 to 250 μmol L), excellent sensitivity (0.024 ± 0.001 μA μmol L), low limit of detection (LOD = 0.7 μmol L), and recovery values from 82 to 115% for beverage samples (white and red wines, beer, water, and vodka) spiked with the abused drug ketamine.
据报道，使用由回收聚乳酸（rPLA）、石墨（Gpt）和炭黑（CB）的混合物组成的自制导电丝材制造的3D打印电极，用于快速检测滥用药物氯胺酮。首先，将这些电极的性能与使用市售导电丝材生产的3D打印电极进行了比较评估。经过一个简单的预处理步骤（机械抛光）后，新型3D打印电极在氧化还原探针的峰峰分离（分别为130 mV和759 mV）、电荷转移电阻（R分别为1.04±0.05 kΩ和9.62±0.03 kΩ）以及异质速率常数（k分别为7.16±0.05×10 cm s和3.57±0.03×10 cm s）方面表现优于由商业丝材生产的电极。实现了氯胺酮检测的优异分析特性，包括宽线性范围（10至250 μmol L）, 出色的灵敏度（0.024±0.001 μA μmol L）、低检测限（LOD = 0.7 μmol L）以及加标滥用药物氯胺酮的饮料样品（白葡萄酒、红葡萄酒、啤酒、水和伏特加）的回收率在82%至115%之间。
