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皮肤紧致度的客观化:300名女性年龄相关的体内评估

Objectification of Skin Firmness: In Vivo Evaluation of 300 Women in Relation to Age.

作者信息

Roessle Alena, Kerscher Martina

机构信息

Cosmetic Science, Institute of Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany.

出版信息

J Cosmet Dermatol. 2025 Jan;24(1):e16773. doi: 10.1111/jocd.16773.

Abstract

BACKGROUND

The concept of "skin quality" (SQ) has gained widespread attention, with a recent international consensus defining it and outlining four "emergent perceptual categories" (EPCs), each accompanied by specific parameters and associated measurement methods. No research has confirmed whether the parameters linked to these EPCs vary objectively with age. This gap in data is significant, as understanding how these parameters correlate with age could be essential for creating an objective, age-adjusted classification of SQ.

AIM

The aim of this study was to investigate the EPC skin firmness in female facial and non-facial skin in relation to age using biophysical measurements. Reference ranges for objective assessment were determined.

PATIENTS/METHODS: Three hundred healthy women (20-69 years) were divided into five age groups. The correlation between age and skin firmness measured by Cutometer and Corneometer (Courage+Khazaka electronic GmbH, Cologne, Germany) devices was evaluated across five anatomical sites: forehead, cheek, neck, décolleté, and the hand. Percentiles were used to generate reference ranges.

RESULTS

Statistical analysis discloses that R2 (U/U), R5 (U/U), and R7 (U/U) correlated with age for all five sites and are preferably assigned to the EPC skin firmness, whereby R2 and R7 showed the strongest correlation. For the neck, significant age-related changes were found in most of the Cutometer parameters. The stratum corneum (SC) hydration showed only low correlations with age.

CONCLUSIONS

R2, R5, and R7 are reliable indicators of age-related changes in skin firmness, with established reference ranges that can aid in treatment decisions and SQ assessments.

摘要

背景

“皮肤质量”(SQ)的概念已受到广泛关注,最近一项国际共识对其进行了定义,并概述了四个“新兴感知类别”(EPC),每个类别都有特定参数和相关测量方法。尚无研究证实与这些EPC相关的参数是否随年龄客观变化。这一数据缺口意义重大,因为了解这些参数与年龄的相关性对于创建客观的、根据年龄调整的SQ分类可能至关重要。

目的

本研究旨在使用生物物理测量方法,调查女性面部和非面部皮肤中与年龄相关的EPC皮肤紧致度。确定客观评估的参考范围。

患者/方法:300名健康女性(20 - 69岁)分为五个年龄组。在五个解剖部位评估年龄与通过Cutometer和Corneometer(德国科隆的Courage+Khazaka电子有限公司)设备测量的皮肤紧致度之间的相关性:额头、脸颊、颈部、胸部和手部。使用百分位数生成参考范围。

结果

统计分析表明,R2(U/U)、R5(U/U)和R7(U/U)在所有五个部位均与年龄相关,且最好归类于EPC皮肤紧致度,其中R2和R7显示出最强的相关性。对于颈部而言,大多数Cutometer参数均发现与年龄相关的显著变化。角质层(SC)水合作用与年龄的相关性较低。

结论

R2、R5和R7是与年龄相关的皮肤紧致度变化的可靠指标,其既定参考范围有助于治疗决策和SQ评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae64/11712028/9278dbd741c2/JOCD-24-e16773-g003.jpg

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