Raju Aleena, Jothish Subhiksha, Sakthivel Kokila, Mishra Shachi, Gana R J, Kikushima Kotaro, Dohi Toshifumi, Singh Fateh V
Department of Chemistry, SAS, Vellore Institute of Technology, Chennai, Tamil Nadu 600127, India.
P. G. Department of Chemistry, Jai Prakash University, Chapra, Saran, Bihar 841302, India.
R Soc Open Sci. 2025 Jan 8;12(1):241215. doi: 10.1098/rsos.241215. eCollection 2025 Jan.
Oxidation reactions are vital tools in synthetic organic chemistry. Oxidation of organic species such as alcohols, phenols, aldehydes and ketones provides synthetically valuable organic compounds, especially synthetic intermediates for several biologically active compounds. Some of these synthetic intermediates have shown their synthetic utility in the total synthesis of natural products. Several classical and modern synthetic approaches have been used to achieve these oxidation reactions. In this review article, various oxidation reactions achieved by metal catalysis are highlighted.
氧化反应是有机合成化学中的重要工具。醇、酚、醛和酮等有机物种的氧化可提供具有合成价值的有机化合物,尤其是几种生物活性化合物的合成中间体。其中一些合成中间体已在天然产物的全合成中展现出其合成效用。人们已采用多种经典和现代合成方法来实现这些氧化反应。在这篇综述文章中,重点介绍了通过金属催化实现的各种氧化反应。