Rezaei Reza, Amir Fakhrian Seyed Hamed, Mehri Ali, Fattahi Masoum Seyed Hossein
Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of General Surgery, Zahedan University of Medical Sciences, Mashhad, Iran.
Kardiochir Torakochirurgia Pol. 2024 Dec;21(4):223-228. doi: 10.5114/kitp.2024.145848. Epub 2024 Dec 12.
Chest wall tumors, though rare, represent a significant subset of thoracic neoplasms, accounting for approximately 5% of thoracic and 2% of overall body neoplasms. Their management has historically posed challenges for surgeons, often leading to misdiagnosis, incomplete resection, and high complication rates. An individualized surgical approach, tailored to the specific characteristics of the disease, is crucial for optimizing outcomes.
To evaluate the outcomes of chest wall masses and report on individual cases.
This retrospective cohort study included 131 patients diagnosed with chest wall masses at Ghaem University Hospital between 2011 and 2021. Data on demographics (age, gender), pre- and post-operative pathology, specific surgical procedures performed, duration of hospitalization, need for post-surgical reconstruction (e.g., flap reconstruction), and history of pre-operative chemotherapy/radiotherapy were collected from medical records. Data were analyzed using descriptive statistics and appropriate inferential tests depending on the variable type. Potential limitations such as missing data or selection bias were acknowledged.
A total of 131 patient records were examined, with an average age of 17.35 ±38.51 years. Of these, 50 (38.2%) were female and 81 (61.8%) were male. It was found that 54.2% of patients had benign tumors, while 45.8% had malignant tumors. Sarcoma (26%) and fibromatosis (21.4%) were the most common tumor types. No significant associations were observed between gender or history of chemotherapy and radiotherapy and the type of surgery performed ( > 0.05). However, a significant association was found between tumor histology and the type of surgery performed ( < 0.05).
The majority of procedures performed were for fibromatous and benign tumors, while the most common malignant tumors were sarcomas, with chondrosarcoma being the predominant subtype. Tumor type significantly influenced the extent of resection and need for chest wall reconstruction.
胸壁肿瘤虽然罕见，但却是胸部肿瘤的一个重要子集，约占胸部肿瘤的5%，占全身肿瘤的2%。其治疗在历史上一直给外科医生带来挑战，常常导致误诊、切除不完全和高并发症发生率。针对疾病的特定特征采取个性化的手术方法对于优化治疗效果至关重要。
评估胸壁肿块的治疗效果并报告个别病例。
这项回顾性队列研究纳入了2011年至2021年间在加姆大学医院被诊断为胸壁肿块的131例患者。从病历中收集了人口统计学数据（年龄、性别）、术前和术后病理、所进行的具体手术程序、住院时间、术后重建需求（如皮瓣重建）以及术前化疗/放疗史。根据变量类型，使用描述性统计和适当的推断性检验对数据进行分析。承认了数据缺失或选择偏倚等潜在局限性。
共检查了131份患者记录，平均年龄为17.35±38.51岁。其中，50例（38.2%）为女性，81例（61.8%）为男性。发现54.2%的患者患有良性肿瘤，而45.8%患有恶性肿瘤。肉瘤（26%）和纤维瘤病（21.4%）是最常见的肿瘤类型。在性别或化疗和放疗史与所进行的手术类型之间未观察到显著关联（>0.05）。然而，在肿瘤组织学与所进行的手术类型之间发现了显著关联（<0.05）。
所进行的大多数手术是针对纤维瘤性和良性肿瘤，而最常见的恶性肿瘤是肉瘤，其中软骨肉瘤是主要亚型。肿瘤类型显著影响切除范围和胸壁重建需求。
