Seyedi-Sahebari Sepideh, Amirhoushangi Hadi, Rasouli Sami, Hasanzadeh Golrokh, Imani Ali, Naseri Amirreza, Nikniaz Leila, Golabi Behnam, Frounchi Negin, Montazer Majid
Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Istanbul Atlas University, Istanbul, Turkey.
Ann Med Surg (Lond). 2025 Mar 7;87(5):2889-2895. doi: 10.1097/MS9.0000000000003125. eCollection 2025 May.
Chest wall masses can be caused by trauma, infections, inflammation, or cancer. These tumors can be benign or malignant and originate from different structures of the chest wall. This systematic review aimed to investigate the histopathological characteristics of chest wall masses. The study followed the PRISMA guidelines. PubMed, Scopus, and Web of Science databases were searched for case series that reported the histopathological features of chest wall masses, without any restrictions on the date. The risk of bias was assessed using the JBI critical appraisal tools. Nine studies were included in the final review. Studies included a total of 1,279 patients with chest wall masses, with diverse age ranges. Biopsy methods such as fine-needle aspiration biopsy (FNAB), cutting needle biopsy, and surgical resection biopsy were used to evaluate the pathology of the masses. The rate of malignancy in chest wall masses varied depending on the biopsy method used, ranging from 27.12% in needle biopsy to 47.16% in surgical resection biopsy. The overall rate of malignancy in chest wall tumors was 31.27%. About one-third of the chest wall masses are malignant, emphasizing the importance of accurate diagnosis and appropriate treatment selection. Choosing the proper biopsy method is crucial for achieving successful outcomes and reducing mortality rates. Further research with larger sample sizes and improved reporting is needed to enhance our understanding of chest wall tumor pathology and improve patient outcomes.
胸壁肿块可由创伤、感染、炎症或癌症引起。这些肿瘤可以是良性的，也可以是恶性的，起源于胸壁的不同结构。本系统评价旨在研究胸壁肿块的组织病理学特征。该研究遵循PRISMA指南。在PubMed、Scopus和Web of Science数据库中检索报告胸壁肿块组织病理学特征的病例系列，对日期无任何限制。使用JBI批判性评价工具评估偏倚风险。最终评价纳入了9项研究。研究共纳入1279例胸壁肿块患者，年龄范围各异。采用细针穿刺活检（FNAB）、切割针活检和手术切除活检等活检方法评估肿块的病理情况。胸壁肿块的恶性率因所用活检方法而异，从针吸活检的27.12%到手术切除活检的47.16%不等。胸壁肿瘤的总体恶性率为31.27%。约三分之一的胸壁肿块为恶性，强调准确诊断和选择合适治疗方法的重要性。选择合适的活检方法对于取得成功结果和降低死亡率至关重要。需要进行更大样本量和改进报告的进一步研究，以增进我们对胸壁肿瘤病理学的理解并改善患者预后。
