Fitzgerald O, Hanly J, Callan A, McDonald K, Molony J, Bresnihan B
Br J Rheumatol. 1985 Feb;24(1):6-10. doi: 10.1093/rheumatology/24.1.6.
Ten patients with rheumatoid arthritis and persistent knee synovitis had synovial fluid aspirated through a 14 gauge wide-bore needle followed by joint lavage and intra-articular triamcinolone. This resulted in the removal of variable quantities of intra-articular debris including rice bodies. When compared to a control group of patients, the addition of joint lavage to the standard procedure of aspiration and injection of corticosteroid resulted in more sustained resolution of synovitis after 12 weeks as judged by knee tenderness and circumference, recurrence of effusion, and synovial fluid leucocyte count. This study suggests that knee joint lavage may be a useful adjunct to therapy in rheumatoid arthritis patients having persistent knee synovitis.
10例患有类风湿性关节炎且膝关节滑膜炎持续存在的患者，通过14号粗针抽取滑液，随后进行关节灌洗并注射关节内曲安奈德。这导致清除了不同数量的关节内碎屑，包括米粒体。与对照组患者相比，在抽取滑液和注射皮质类固醇的标准程序中增加关节灌洗，根据膝关节压痛、周长、积液复发情况以及滑液白细胞计数判断，12周后滑膜炎的缓解更持久。这项研究表明，对于患有持续性膝关节滑膜炎的类风湿性关节炎患者，膝关节灌洗可能是一种有用的辅助治疗方法。
