Feun L G, Yung W K, Stewart D J, Savaraj N, Bodey G P
Cancer Treat Rep. 1985 Mar;69(3):329-30.
Sixteen patients with primary malignant brain tumors, recurrent or progressive after surgery and radiation therapy, were treated with mitoguazone. Starting dose was 500 mg/m2 iv on a weekly schedule. In 15 evaluable patients no tumor regressions were observed. Four patients had stabilization of disease.
16例原发性恶性脑肿瘤患者,术后及放疗后复发或病情进展,接受了丙脒腙治疗。起始剂量为500mg/m²,静脉注射,每周一次。15例可评估患者均未观察到肿瘤缩小。4例患者病情稳定。