Negera Atoma, Sento Midekso, Dereje Debela, Firdisa Gamachis, Negera Samuel, Nenko Geleta, Sime Tadesse, Keba Merga
Nursing Department, College of Health Science, Mattu University, Mattu Town, Oromia Regional State, Ethiopia.
Biomedical Department, Anatomy Course Unit, Adama Hospital Medical College, Adama Town, Oromia Regional State, Ethiopia.
PLoS One. 2025 Jan 9;20(1):e0313923. doi: 10.1371/journal.pone.0313923. eCollection 2025.
Diaper dermatitis (DD, sometimes known as diaper rash or napkin dermatitis is one of the most prevalent skin infections that occur in the area covered by the diaper. Although diaper dermatitis can be seen in any patient wearing diapers, it is reported to be more common in infants aged 9-12 months. Approximately, 70% of infants and young children suffer from diaper dermatitis at some point during their diaper wearing years and up to 25% of children seek healthcare due to this case.
METHODS AND ANALYSIS: A comprehensive literature search will be gathered from electronic databases such as PubMed, Embase, Hinari, Cochrane Library, African Journals Online (AJOL), and Google Scholar. The protocol followed the Preferred Reporting Items for Systematic Reviews and Meta-analyses for Protocol (PRISMA-P) guideline. All studies conducted in low- and middle-income countries (LMICs) will be included regardless of their study design as long as these studies report the magnitude of the problem under study. Joanna Briggs Institute's (JBI) appraisal checklist will be used to assess the quality of individual studies. Heterogeneity will be checked using Cochrane Q test statistics and I2 test statistics, and a random-effects model will be employed to estimate the pooled prevalence of DD and its associated factors.
Ethics committee approval or written informed consent will not be required to conduct this review, and meta-analysis for the review will be entirely based on published data. The result of this study will be submitted to a peer-reviewed journal, and it will also be presented at relevant research conferences.
The present study will estimate the pooled prevalence of diaper dermatitis and their associated factors in low- and middle-income countries.
PROSPERO registration number: CRD42024578550.
尿布皮炎（DD，有时也称为尿布疹或尿片皮炎）是尿布覆盖区域最常见的皮肤感染之一。尽管任何使用尿布的患者都可能出现尿布皮炎，但据报道在9至12个月大的婴儿中更为常见。大约70%的婴幼儿在使用尿布期间的某个阶段会患上尿布皮炎，多达25%的儿童因该病寻求医疗护理。
将从电子数据库如PubMed、Embase、Hinari、Cochrane图书馆、非洲在线期刊（AJOL）和谷歌学术等收集全面的文献检索。该方案遵循系统评价与Meta分析方案的首选报告项目（PRISMA-P）指南。所有在低收入和中等收入国家（LMICs）进行的研究都将被纳入，无论其研究设计如何，只要这些研究报告了所研究问题的严重程度。将使用乔安娜·布里格斯研究所（JBI）的评估清单来评估个体研究的质量。将使用Cochrane Q检验统计量和I2检验统计量检查异质性，并采用随机效应模型来估计尿布皮炎及其相关因素的合并患病率。
进行本综述无需伦理委员会批准或书面知情同意，且该综述的Meta分析将完全基于已发表的数据。本研究结果将提交给同行评审期刊，并在相关研究会议上展示。
本研究将估计低收入和中等收入国家尿布皮炎及其相关因素的合并患病率。
PROSPERO注册号：CRD42024578550。
