Individual and combined effects of noise exposure and diabetes mellitus on hearing.

Hearing loss (HL) is a prevalent health concern with a significant impact on society and the economy. Several factors contribute to the development of hearing impairment, with noise overexposure being the primary culprit. Diabetes mellitus (DM) is also a factor in hearing impairment, and studies have shown a positive correlation between DM and HL; however, the exact causal relationship and pathogenesis remain contentious. Given the ubiquity of noise exposure and the high incidence of DM, individuals may develop diabetes while being chronically exposed to noise. It is particularly important to explore the independent and combined effects of noise and DM on hearing, which can help healthcare professionals understand the potential risks posed by these factors and inspire prevention strategies and potential interventions for hearing impairment. This review summarizes the current research advancements in noise-induced HL and diabetes-related HL and discusses their characteristics and potential mechanisms. Furthermore, this review focuses on the combined effects of noise exposure and DM on hearing, setting the stage for further research and development of intervention strategies to address HL.