Chromik Lindsay C, Friedman Lauren M, Fabrikant-Abzug Gabrielle, Davis Mary C, Doane Leah D, Lemery-Chalfant Kathryn
Department of Psychology, Arizona State University, USA.
Department of Psychology, Arizona State University, USA.
Infant Behav Dev. 2025 Mar;78:102025. doi: 10.1016/j.infbeh.2024.102025. Epub 2025 Jan 8.
Early intervention is effective for reducing ADHD symptoms and related impairments, yet methods of identifying young children in need of services are lacking. Most early predictors of ADHD previously identified are of limited clinical utility. This study examines several theoretically relevant predictors of ADHD in infancy and toddlerhood and whether assessment at multiple time points improves prediction. We also examine whether links between early risk factors and middle childhood ADHD are driven by shared genetic and/or environmental mechanisms to identify potential early intervention targets.
614 twins (52.12 % female, 58.50 % non-Hispanic White) participated in a larger study on genetic and environmental contributions to mental health outcomes. Caregiver-reported attention and behavior problems in infancy (M = 12.67 months) and toddlerhood (M = 32.18 months) and caregiver-reported temperament (attentional focusing, impulsivity, inhibitory control) in toddlerhood were used to predict caregiver-reported ADHD symptoms in middle childhood (M = 8.78 years).
Only behavior problems in infancy and toddlerhood were robust predictors of caregiver-reported ADHD symptoms in middle childhood. Using multiple timepoints did not improve predictive ability. The relationship between infant behavior problems and caregiver reported middle childhood ADHD symptoms was explained by both environmental and genetic influences, whereas environmental influences almost entirely explained the relationship between toddler behavior problems and caregiver-reported middle childhood ADHD symptoms.
Behavior problems in toddlerhood showed the strongest predictive utility, and links to later ADHD were largely driven by environmental factors, suggesting that psychosocial interventions modifying the child's environment may be particularly effective for reducing ADHD risk.
早期干预对于减轻注意力缺陷多动障碍(ADHD)症状及相关损害是有效的,但缺乏识别需要服务的幼儿的方法。先前确定的大多数ADHD早期预测因素的临床效用有限。本研究考察了婴幼儿期ADHD的几个理论上相关的预测因素,以及多个时间点的评估是否能改善预测。我们还考察了早期风险因素与童年中期ADHD之间的联系是否由共同的遗传和/或环境机制驱动,以确定潜在的早期干预目标。
614对双胞胎(52.12%为女性,58.50%为非西班牙裔白人)参与了一项关于遗传和环境对心理健康结果影响的更大规模研究。使用照顾者报告的婴儿期(平均年龄12.67个月)和幼儿期(平均年龄32.18个月)的注意力和行为问题,以及照顾者报告的幼儿期气质(注意力集中、冲动性、抑制控制)来预测照顾者报告的童年中期(平均年龄8.78岁)的ADHD症状。
只有婴儿期和幼儿期的行为问题是照顾者报告的童年中期ADHD症状的有力预测因素。使用多个时间点并没有提高预测能力。婴儿期行为问题与照顾者报告的童年中期ADHD症状之间的关系由环境和遗传影响共同解释,而环境影响几乎完全解释了幼儿期行为问题与照顾者报告的童年中期ADHD症状之间的关系。
幼儿期的行为问题显示出最强的预测效用,且与后期ADHD的联系在很大程度上由环境因素驱动,这表明改变儿童环境的心理社会干预措施可能对降低ADHD风险特别有效。