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基于重症医学和免疫学的多学科整合与融合:历史、现状与展望

Multidisciplinary integration and fusion based on critical care medicine and immunology: History, current status, and prospects.

作者信息

Shi Jian, Lü Ben

机构信息

Third Xiangya Hospital, Central South University, Changsha 410013.

Second Xiangya Hospital, Central South University, Changsha 410011, China.

出版信息

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2024 Aug 28;49(8):1327-1332. doi: 10.11817/j.issn.1672-7347.2024.240220.

Abstract

Critical care medicine focuses on understanding the pathophysiological mechanisms and treatment approaches for life-threatening conditions, including sepsis, severe trauma/burns, hemorrhagic shock, heatstroke, and acute pancreatitis, all of which have high incidence rates. These conditions are primarily characterized by acute multi-organ dysfunction, with sudden onset, severe illness, and high mortality rates. Additionally, critical care treatment demands substantial medical resources, imposing significant economic burdens on patients' families and society. In recent years, critical care medicine has achieved notable progress, especially in multidisciplinary integration with immunology-based fields. Collaboration across disciplines has not only accelerated advancements in critical care but also propelled the rapid development of modern immunology. This paper provides an overview and assessment of the cross-disciplinary fusion between critical care medicine and immunology, exploring how these fields related extensions mutually enhance each other. It further analyzes China's potential to become a global leader in this area within the next 5 to 10 years.

摘要

重症医学专注于理解危及生命状况的病理生理机制和治疗方法,这些状况包括脓毒症、严重创伤/烧伤、失血性休克、中暑和急性胰腺炎,所有这些疾病的发病率都很高。这些病症主要以急性多器官功能障碍为特征,具有起病急、病情严重和死亡率高的特点。此外,重症治疗需要大量医疗资源,给患者家庭和社会带来巨大经济负担。近年来,重症医学取得了显著进展,尤其是在与基于免疫学领域的多学科整合方面。跨学科合作不仅加速了重症医学的进步,也推动了现代免疫学的快速发展。本文对重症医学与免疫学之间的跨学科融合进行了概述和评估,探讨了这些领域如何相互促进、共同发展。本文还进一步分析了中国在未来5至10年内成为该领域全球领先者的潜力。

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