通过双芳炔插入碳-硫双键由硫脲合成噻吨酮
Thioxanthone Synthesis from Thioureas through Double Aryne Insertion into a Carbon-Sulfur Double Bond.
作者信息
Kawada Mayu, Tabata Shinya, Hoshi Yukitaka, Yoshida Suguru
机构信息
Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan.
出版信息
Org Lett. 2025 Jan 24;27(3):827-832. doi: 10.1021/acs.orglett.4c04490. Epub 2025 Jan 9.
Thioxanthone synthesis from -silylaryl triflates and thioureas is disclosed. Double aryne insertion into the C═S double bond of thioureas and subsequent hydrolysis realized the facile preparation of thioxanthones. A simple reaction procedure and good accessibility of -silylaryl triflates allowed us to synthesize a wide range of highly functionalized thioxanthones.
公开了由 - 甲硅烷基芳基三氟甲磺酸酯和硫脲合成噻吨酮的方法。双芳炔插入硫脲的C═S双键并随后水解实现了噻吨酮的简便制备。简单的反应程序以及 - 甲硅烷基芳基三氟甲磺酸酯的良好可得性使我们能够合成多种高度官能化的噻吨酮。
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