Roy Tony, Biju Akkattu T
Organic Chemistry Division, CSIR-National Chemical Laboratory (CSIR-NCL), Dr. Homi Bhabha Road, Pune-411008, India.
Chem Commun (Camb). 2018 Mar 8;54(21):2580-2594. doi: 10.1039/c7cc09122b.
This Feature Article is aimed at highlighting the recent developments in the transition-metal-free molecular rearrangements involving arynes. The chemistry of arynes has shown incredible developments especially in transition-metal-free carbon-carbon and carbon-heteroatom bond-forming reactions in the last three decades. The rapid growth in this field is mainly due to the development of mild methods for the generation of arynes. One aspect of the recent developments in the chemistry of arynes involves the molecular rearrangements proceeding via this electrophilic intermediate. The molecular rearrangements have provided direct access to a library of valuable molecules, which cannot be accessed in a single step through other synthetic routes. Herein, we present a concise account on the developments that occurred in this field over the last three decades.
这篇专题文章旨在突出涉及芳炔的无过渡金属分子重排的最新进展。在过去三十年中，芳炔化学展现出了令人难以置信的发展，尤其是在无过渡金属的碳 - 碳和碳 - 杂原子成键反应方面。该领域的快速发展主要归功于温和的芳炔生成方法的开发。芳炔化学近期发展的一个方面涉及通过这种亲电中间体进行的分子重排。分子重排为一系列有价值的分子库提供了直接的合成途径，而这些分子无法通过其他合成路线一步获得。在此，我们简要介绍过去三十年来该领域所取得的进展。
